Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862671 | 0.81 | HCAR1 (0.47) | KMT2AHTTHSD17B10HCAR1ALDH1A1 | |
| SCHEMBL30426426 | 0.77 | ALDH1A1 (0.52) | KMT2AHTTHSD17B10HCAR1ALDH1A1 | |
| SCHEMBL5242261 | 0.77 | ALDH1A1 (0.52) | KMT2AHTTHSD17B10HCAR1ALDH1A1 | |
| SCHEMBL31716936 | 0.75 | TSHR (0.55) | KMT2AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL20766723 | 0.75 | ALDH1A1 (0.37) | KMT2AHTTALDH1A1L3MBTL1MAPT | |
| SCHEMBL17743399 | 0.75 | ALDH1A1 (0.53) | KMT2AHTTHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL10550799 | 0.73 | HCAR1 (0.47) | KMT2AHTTHSD17B10HCAR1ALDH1A1 | |
| SCHEMBL9179941 | 0.73 | KMT2A (0.38) | KMT2AHTTHSD17B10HCAR1ALDH1A1 | |
| SCHEMBL1274938 | 0.72 | HTT (0.73) | KMT2AHTTALDH1A1L3MBTL1MAPT | |
| SCHEMBL1320968 | 0.72 | GRIK1 (0.49) | KMT2AHTTHSD17B10HCAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |