Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.49 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.49 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444848 | 1.00 | GRIK1 (0.49) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10550799 | 0.80 | HCAR1 (0.47) | MAPTHSD17B10KMT2AHTTALDH1A1 | |
| SCHEMBL990709 | 0.78 | GRIA1 (0.54) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6677996 | 0.77 | GAA (0.57) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27635265 | 0.77 | AR (0.61) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27708625 | 0.77 | GRIK1 (0.51) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL3477968 | 0.77 | MAPT (0.61) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28839186 | 0.77 | TDP1 (0.52) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9044798 | 0.76 | TSHR (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL20816305 | 0.76 | TDP1 (0.50) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143104-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2023-12-01 | — | — | CN | claimed |
| CN-115155640-B | Molybdenum catalyst, catalytic composition and application thereof in preparation of amine compounds | 海南华瑞医药有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-105866441-A | Method for detecting concentration of estrogen or estrogenic-like compound | 中国科学院生态环境研究中心 | 2016-08-17 | — | — | CN | claimed |
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-12-22 | — | — | US | claimed |
| WO-2010097815-A2 | A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | claimed |
| CN-115677708-B | Pyrrolo-quinoxaline Process for the preparation of a pinine | 深圳万知达企业管理有限公司 | 2024-11-29 | — | — | CN | disclosed |
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | University of Florida Research Fooundation, Incorporated (US) | 2024-07-25 | — | — | US | disclosed |
| CN-117143104-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-115322200-B | Preparation method of spiro pyrroloquinoxaline derivative | 五邑大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-115155640-B | Molybdenum catalyst, catalytic composition and application thereof in preparation of amine compounds | 海南华瑞医药有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116082344-A | Phenyl butanone substituted pyrrolo [1,2-a ] quinoxaline compound and preparation method thereof | 宁夏医科大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-115677708-A | Preparation method of pyrroloquinoxaline | 五邑大学 | 2023-02-03 | — | — | CN | disclosed |
| US-4697001-A | OXIDATION CAUSING POLYMERIZATION | ROCKWELL INTERNATIONAL CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |
| US-4696835-A | Process for applying an electrically conducting polymer to a substrate | ROCKWELL INTERNATIONAL CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |
| US-4617228-A | PRECIPITATING AND DOPING POLYPYRROLES IN POROUS MATERIAL; STRONG OXIDANT AND NON-NUCLEOPHILIC ANIONS | ROCKWELL INTERNATIONAL CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |
| US-4582575-A | Electrically conductive composites and method of preparation | ROCKWELL INTERNATIONAL CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0055358-B1 | ELECTROCONDUCTIVE POLYPYRROLE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |
| US-4401545-A | COMPLEXED WITH NITRO-AROMATIC COMPOUND | BASF AKTIENGESELLSCHAFT (US) | 1983-08-30 | — | — | US | disclosed |
| EP-0055358-A1 | Electroconductive polypyrrole derivatives | BASF Aktiengesellschaft (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-3939159-A | ANTICONVULSANT, CNS DEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | IL6, IL6ST, IL36G | GRIK1 3240/4885GRIA1 3426/4885GRIA2 3406/4885 |
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | HCN2, RAC2, HCN1 | GRIK1 1094/4885GRIA1 497/4885GRIA2 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.