Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485787 | 0.91 | ALDH1A1 (0.57) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| SCHEMBL8622494 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNATDP1MEN1 | |
| SCHEMBL8184057 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| Glutarate SCHEMBL28719278 | 0.81 | TSHR (0.56) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| SCHEMBL28528160 | 0.80 | LPAR3 (0.44) | ALDH1A1PPARD | |
| SCHEMBL1487740 | 0.78 | PPARD (0.57) | ALDH1A1TSHRSLC22A6AKR1B1GPR84 | |
| SCHEMBL3471394 | 0.77 | LMNA (0.43) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| SCHEMBL234493 | 0.77 | LMNA (0.43) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| SCHEMBL12473687 | 0.77 | LMNA (0.43) | ALDH1A1TSHRLMNASLC22A6NFKB1 | |
| SCHEMBL2385908 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109576236-A | A kind of D-AAO mutant and its application | 浙江工业大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-108795835-A | A kind of genetic engineering bacterium and its application in preparing L-glufosinate-ammonium | 浙江大学 | 2018-11-13 | — | — | CN | disclosed |
| EP-2686342-A2 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | The Government of The United States of America, as represented by The Secretary, Department of Health and Human Services (US) | 2014-01-22 | — | — | EP | disclosed |
| WO-2012142245-A2 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | THE GOVERNMENT OF THE UNITED OF AMERIA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2012-10-18 | — | — | WO | disclosed |
| EP-2125017-A2 | MODULATION OF NEUROGENESIS WITH USE OF MODAFINIL | Braincells, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008086483-A2 | MODULATION OF NEUROGENESIS WITH USE OF MODAFINIL | BRAINCELLS, INC. (US) | 2008-07-17 | — | — | WO | disclosed |