Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453714 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL8622494 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNATDP1MEN1 | |
| SCHEMBL25899667 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL4283089 | 0.80 | PPARD (0.53) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL13743103 | 0.80 | PPARD (0.53) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL7172938 | 0.79 | TSHR (0.50) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL3473015 | 0.79 | TSHR (0.50) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL18096846 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL28008096 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL22909149 | 0.79 | LPAR1 (0.38) | ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029903-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2010-02-04 | — | — | US | disclosed |
| EP-1963343-A1 | POLYPEPTIDE PROTRACTING TAGS | Novo Nordisk A/S (DK) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007068718-A1 | POLYPEPTIDE PROTRACTING TAGS | NOVO NORDISK A/S (DK) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029903-A1 | Polypeptide Protracting Tags | LAS1L, SEC16A, PHAX | ALDH1A1 3822/4885TSHR 849/4885LMNA 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.