SCHEMBL4453723

SCHEMBL4453723

Cc1ccc(S(=O)(=O)C(C)(C)Cc2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.51
CA12 O43570 2/20 0.51
CA9 Q16790 2/20 0.51
BCHE P06276 1/20 0.51
ACHE P22303 1/20 0.51
CYP1A2 P05177 1/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MCHR1 Q99705 1/20 0.49
ALDH1A1 P00352 3/20 0.48
CNR2 P34972 3/20 0.45
MMP1 P03956 1/20 0.45
MMP9 P14780 1/20 0.45
MMP13 P45452 1/20 0.45
KMT2A Q03164 3/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 2/20 0.43
CA2 P00918 2/20 0.43
CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28317049 0.85 RECQL (0.48) CA12CA9ALDH1A1MMP1MMP9
Benzophenone SCHEMBL28662812 0.81 RECQL (0.44) CA12CA9ALDH1A1MMP1MMP9
SCHEMBL28026558 0.79 SMN1; SMN2 (0.49) CYP3A4CA12CA9BCHEACHE
SCHEMBL28026557 0.79 SMN1; SMN2 (0.49) CYP3A4CA12CA9BCHEACHE
SCHEMBL3416574 0.79 RECQL (0.42) CA12CA9ALDH1A1MMP1MMP13
SCHEMBL28225624 0.79 RECQL (0.42) CA12CA9ALDH1A1MMP1MMP9
SCHEMBL12143763 0.77 ALDH1A1 (0.50) CYP3A4CA12CA9BCHEACHE
SCHEMBL6820712 0.77 ATM (0.58) CYP3A4CA12CA9BCHEACHE
SCHEMBL31172118 0.77 SLC6A2 (0.52) CYP3A4CA12CA9CYP1A2ALDH1A1
SCHEMBL1667314 0.76 MEN1 (0.40) CYP3A4CA12CA9BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090072207-A1 FLAME RETARDANT RESIN COMPOSITION FOR PRINTED CIRCUIT BOARD, PRINTED CIRCUIT BOARD USING THE SAME AND MANUFACTURING METHOD THEREOF SAMSUNG ELECTRO-MECHANICS CO., LTD. 2009-03-19 US disclosed
US-20040076909-A1 Colour changing composition and colouring polymeric articles made therefrom SHIRLEY DIANNE BETH (GB) 2004-04-22 US disclosed
EP-1103017-B1 COLOUR CHANGING COMPOSITION AND COLOURING POLYMERIC ARTICLES MADE THEREFROM VANTICO LTD (GB) 2004-02-25 EP disclosed
US-6649311-B1 Dispersed Microcapsules containing a photosensitive colour changing composition; cationic photoinitiators; stereolithography VANTICO LIMITED (GB) 2003-11-18 US disclosed
EP-0854783-B1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS VANTICO LTD (GB) 2002-10-23 EP disclosed
EP-1103017-A1 COLOUR CHANGING COMPOSITION AND COLOURING POLYMERIC ARTICLES MADE THEREFROM Vantico Limited (GB) 2001-05-30 EP disclosed
US-6133336-A FORMING A SELECTIVELY COLORED POLYMERIC LAYER, OR A THREE-DIMENSIONAL ARTICLE MADE OF POLYMERIC LAYERS, WHEREIN A PHOTOCURABLE PHOTOCOLORABLE COMPOSITION IS IRRADIATED WITH A LOW DOSE OF LIGHT TO CURE AND A HIGHER DOSE OF LIGHT TO COLOR ZENECA LIMITED (GB) 2000-10-17 US disclosed
WO-2000007071-A1 COLOUR CHANGING COMPOSITION AND COLOURING POLYMERIC ARTICLES MADE THEREFROM VANTICO LIMITED (GB) 2000-02-10 WO disclosed
EP-0854783-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1998-07-29 EP disclosed
WO-1997009168-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1997-03-13 WO disclosed