⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940561 | 0.70 | — | — | |
| SCHEMBL4481600 | 0.67 | — | — | |
| SCHEMBL2016827 | 0.63 | — | — | |
| Methane SCHEMBL190374 | 0.61 | — | — | |
| Methane SCHEMBL222390 | 0.61 | — | — | |
| SCHEMBL2221687 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL1554036 | 0.61 | — | — | |
| SCHEMBL8526267 | 0.50 | — | — | |
| SCHEMBL4324422 | 0.49 | — | — | |
| SCHEMBL7215897 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569658-A | Sulfonyl pyridazinone compound and preparation method and application thereof | 华南师范大学 | 2025-03-07 | — | — | CN | claimed |
| JP-52003081-A | — | — | None | — | — | JP | disclosed |
| CN-119569658-A | Sulfonyl pyridazinone compound and preparation method and application thereof | 华南师范大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-119569658-A | Sulfonyl pyridazinone compound and preparation method and application thereof | 华南师范大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-119569658-A | Sulfonyl pyridazinone compound and preparation method and application thereof | 华南师范大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-119528662-A | Preparation method of trans-S-alkenyl thio pyridazine compound | 常州大学 | 2025-02-28 | — | — | CN | disclosed |
| US-7572910-B2 | Pyridazinone aldose reductase inhibitors | PFIZER, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1491541-B1 | Pyridazinone aldose reductase inhibitors | PFIZER PROD INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1491540-B1 | Intermediates useful for the synthesis of pyridazinone aldose reductase inhibitors | PFIZER PROD INC (US) | 2006-12-13 | — | — | EP | disclosed |
| EP-1463725-B1 | PROCESS AND INTERMEDIATES FOR PYRIDAZINONE ANTIDIABETIC AGENTS | PFIZER PROD INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1260224-A1 | Sulfonyl pyridazinone compounds as therapeutic agents for ischemic tissue damage | Pfizer Products Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2002087584-A1 | COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND CYCLOOXYGENASE-2 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002079198-A1 | PYRIDAZINONE ALDOSE REDUCTASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2002-10-10 | — | — | WO | disclosed |
| US-20020143017-A1 | Pyridazinone aldose reductase inhibitors | MYLARI BANAVARA L (US) | 2002-10-03 | — | — | US | disclosed |
| EP-1236720-A1 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors | Pfizer Products Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-1236720-A1 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors | Pfizer Products Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-1007515-A1 | ARYLPYRIDAZINONES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | Abbott Laboratories (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999010331-A1 | ARYLPYRIDAZINONES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 1999-03-04 | — | — | WO | disclosed |
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| JP-S523081-A | PREPARATION OF SULFONYLPYRIDAZIONONES | MORISHITA SEIYAKU KK | 1977-01-11 | — | — | JP | disclosed |