SCHEMBL4454010

SCHEMBL4454010

CC(Oc1ccc(N)cc1)C(=O)OCCOCC(=O)COc1ccc(N)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 2/20 0.42
GAA P10253 1/20 0.42
LMNA P02545 1/20 0.42
PLA2G4B P0C869 10/20 0.41
PLA2G4A P47712 1/20 0.36
KMT2A Q03164 1/20 0.36
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16261864 0.86 TDP1 (0.49) L3MBTL1TDP1GAALMNAKMT2A
SCHEMBL829668 0.85 TDP1 (0.46) L3MBTL1TDP1GAALMNAKMT2A
SCHEMBL829850 0.85 LMNA (0.47) L3MBTL1TDP1GAALMNAKMT2A
SCHEMBL16261865 0.82 L3MBTL1 (0.43) L3MBTL1TDP1GAALMNAAPP
SCHEMBL16270207 0.81 TDP1 (0.46) L3MBTL1TDP1GAALMNAKMT2A
SCHEMBL839428 0.78 LMNA (0.43) L3MBTL1TDP1GAALMNAKMT2A
SCHEMBL12810513 0.77 TDP1 (0.41) L3MBTL1TDP1GAALMNAKMT2A
SCHEMBL17676526 0.75 TDP1 (0.52) L3MBTL1TDP1GAAPLA2G4BPLA2G4A
SCHEMBL658139 0.74 LMNA (0.60) L3MBTL1TDP1GAALMNAKMT2A
SCHEMBL15908118 0.73 L3MBTL1 (0.49) L3MBTL1TDP1GAALMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937182-A4 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2009-07-15 EP disclosed
EP-1937182-A2 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES Bezwada Biomedical LLC (US) 2008-07-02 EP disclosed
WO-2007030464-A2 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2007-03-15 WO disclosed