Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829850 | 0.88 | LMNA (0.47) | LMNAL3MBTL1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6716380 | 0.86 | L3MBTL1 (0.60) | LMNAL3MBTL1KMT2AEPHX2MAPT | |
| SCHEMBL9063261 | 0.86 | LMNA (0.63) | LMNAL3MBTL1KMT2ACYP1A2EPHX2 | |
| SCHEMBL5205374 | 0.86 | LMNA (0.63) | LMNAL3MBTL1KMT2ACYP1A2EPHX2 | |
| SCHEMBL9857703 | 0.86 | LMNA (0.63) | LMNAL3MBTL1KMT2ACYP1A2EPHX2 | |
| SCHEMBL11548487 | 0.86 | L3MBTL1 (0.63) | LMNAL3MBTL1KMT2ACYP1A2EPHX2 | |
| SCHEMBL18562096 | 0.86 | LMNA (0.63) | LMNAL3MBTL1KMT2ACYP1A2EPHX2 | |
| SCHEMBL5112826 | 0.84 | LMNA (0.61) | LMNAL3MBTL1KMT2AEPHX2MAPT | |
| SCHEMBL7692036 | 0.84 | L3MBTL1 (0.61) | LMNAL3MBTL1KMT2ACYP1A2EPHX2 | |
| SCHEMBL9621303 | 0.84 | LMNA (0.66) | LMNAL3MBTL1KMT2ACYP1A2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583874-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024132001-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024132001-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2024-06-27 | — | — | WO | disclosed |
| US-11007193-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2021-05-18 | — | — | US | disclosed |
| US-10828301-B2 | 2,4-pyrimidinediamine compounds and their uses | Rigel Pharmceuticals, Inc. (US) | 2020-11-10 | — | — | US | disclosed |
| US-10709703-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-10682350-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| US-20200085820-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2020-03-19 | — | — | US | disclosed |
| US-20190255047-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2019-08-22 | — | — | US | disclosed |
| US-10369148-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| WO-2003063794-A2 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| US-5235090-A | Synthesis of 2-(4'-aminophenyloxy) alkanoic acids & acids & esters & their derivatives | HOECHST CELANESE CORP. (US) | 1993-08-10 | — | — | US | disclosed |
| US-4883901-A | Synthesis of 2-(4-aminophenoxy)alkanoic acids and esters and their derivatives | HOECHST CELANESE CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0334598-A2 | Synthesis of 2-(4'aminophenoxy) alkanoic acids and esters and their derivatives | HOECHST CELANESE CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0107216-B1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND METHOD OF CONTROLLING UNWANTED PLANT GROWTH | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-10-01 | — | — | EP | disclosed |
| US-4452626-A | Herbicidal 4-(benzotriazol-1-yl)phenoxy)alkanoic acids, esters and salts | SHELL OIL COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0107216-A1 | Heterocyclic compounds, their preparation, compositions containing them and method of controlling unwanted plant growth | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-05-02 | — | — | EP | disclosed |
| US-4439226-A | Herbicidal 4-((benzimidazol-1-yl)phenoxy)alkanoic acids, esters and salts | SHELL OIL COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| US-4358307-A | PREFERENTIAL CONTROLLING OF MONOCOTYLEDONS IN CROPS | ICI AUSTRALIA LIMITED (AU) | 1982-11-09 | — | — | US | disclosed |
| EP-0026622-A2 | Quinoxalinylaminophenoxyalkane carboxylic acid derivatives, their preparation, their use as herbicides and intermediates | ICI AUSTRALIA LIMITED (AU) | 1981-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200085820-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | FCER2, FCGR1A, FCGR2A | LMNA 4827/4885L3MBTL1 4395/4885KMT2A 2984/4885 |
| US-10682350-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | LMNA 4827/4885L3MBTL1 4395/4885KMT2A 2984/4885 |
| US-10709703-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | LMNA 4827/4885L3MBTL1 4395/4885KMT2A 2984/4885 |
| US-10369148-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | LMNA 4827/4885L3MBTL1 4395/4885KMT2A 2984/4885 |
| US-11007193-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | LMNA 4827/4885L3MBTL1 4395/4885KMT2A 2984/4885 |
| US-20190255047-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | FCER2, FCGR1A, FCGR2A | LMNA 4827/4885L3MBTL1 4395/4885KMT2A 2984/4885 |
| US-10828301-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | LMNA 4827/4885L3MBTL1 4395/4885KMT2A 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.