SCHEMBL4454021

SCHEMBL4454021

CC1(C)CC2(CC(C)(C)c3c(Cl)c(Cl)c(O)c(Cl)c32)c2c(Cl)c(O)c(Cl)c(Cl)c21

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4464517 0.69 FTO (0.39) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL298773 0.62 MEN1 (0.41) MEN1ALDH1A1LMNAMAPTHPGD
Pentachlorophenol SCHEMBL3261028 0.61 HSD17B10 (0.91) MEN1ALDH1A1LMNAMAPTHPGD
Tetrachlorohydroquinone SCHEMBL48198 0.61 HSD17B10 (0.90) MEN1ALDH1A1LMNAMAPTHPGD
Pentachlorophenol SCHEMBL28030118 0.59 HSD17B10 (0.83) MEN1ALDH1A1LMNAMAPTHPGD
Pentachlorophenol SCHEMBL23121452 0.58 HSD17B10 (1.00) MEN1ALDH1A1LMNAMAPTHPGD
Pentachlorophenol SCHEMBL1492 0.58 HSD17B10 (1.00) MEN1ALDH1A1LMNAMAPTHPGD
Pentachlorophenol SCHEMBL1330735 0.58 HSD17B10 (1.00) MEN1ALDH1A1LMNAMAPTHPGD
Perchlorobenzene SCHEMBL28269084 0.58 HSD17B10 (1.00) MEN1ALDH1A1LMNAMAPTHPGD
Pentachlorophenol SCHEMBL5315995 0.58 HSD17B10 (1.00) MEN1ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed