Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459436 | 0.84 | HNF4A (0.35) | FTOCYP3A4CYP1A2CYP2C19CHRM1 | |
| SCHEMBL11143859 | 0.80 | FTO (0.35) | FTOTSHRHSD17B10HPGDMAPK1 | |
| SCHEMBL8015643 | 0.78 | CYP3A4 (0.38) | FTOHSD17B10HPGDCYP3A4ESR1 | |
| SCHEMBL13668265 | 0.77 | FTO (0.33) | FTOCYP3A4CYP1A2CYP2C19MEN1 | |
| SCHEMBL24604252 | 0.73 | CYP3A4 (0.30) | CYP3A4CHRM1ALOX15TBXA2RADRA1A | |
| SCHEMBL4462287 | 0.73 | TP53 (0.43) | FTOTSHRMAPK1CYP3A4CYP1A2 | |
| SCHEMBL13712361 | 0.72 | S1PR1 (0.34) | FTO | |
| SCHEMBL30773362 | 0.72 | FTO (0.32) | FTOCYP1A2ACHE | |
| SCHEMBL3256213 | 0.72 | FTO (0.32) | FTOCYP1A2ACHE | |
| SCHEMBL14154436 | 0.71 | FTO (0.42) | FTOTSHRHSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582355-B2 | Optical unit using plastic lenses | FUJIFILM CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| EP-1768943-B1 | PROCESS FOR PREPARING ENANTIOMERICALLY PURE 1,1'-SPIROBIINDANE-6,6'-DIOL DERIVATIVES | IND TECH RES INST (CN) | 2008-12-17 | — | — | EP | disclosed |
| US-7214834-B2 | Process for preparing enantiomerically pure 1,1′-spirobiindane-6,6′-diol derivatives | EASTMAN KODAK COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214834-B2 | Process for preparing enantiomerically pure 1,1′-spirobiindane-6,6′-diol derivatives | EASTMAN KODAK COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-20060046065-A1 | Optical unit using plastic lenses | FUJI PHOTO FILM CO., LTD. | 2006-03-02 | — | — | US | disclosed |
| US-6028161-A | EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER | MITSUI CHEMICALS, INC. (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0926180-A2 | A polycarbonate copolymer and applications thereof | Mitsui Chemicals, Inc. (JP) | 1999-06-30 | — | — | EP | disclosed |