SCHEMBL4454270

SCHEMBL4454270

CCCCCCO[Si](CC)(OCCCCCC)OCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 6/20 0.43
LPAR2 Q9HBW0 5/20 0.43
THRB P10828 2/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.39
CA1 P00915 8/20 0.38
CA2 P00918 8/20 0.38
CA9 Q16790 7/20 0.38
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
LPAR1 Q92633 2/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL826100 1.00 LPAR3 (0.43) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL1609029 0.97 LPAR3 (0.39) LPAR3LPAR2THRBTSHRMEN1
Methylamine SCHEMBL2763140 0.95 CA1 (0.40) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL27876576 0.93 LPAR3 (0.39) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL1494567 0.93 LPAR3 (0.39) LPAR3LPAR2THRBTSHRMEN1
Fluoride SCHEMBL28795057 0.91 LPAR3 (0.38) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL150402 0.89 ADRB2 (0.41) LPAR3LPAR2THRBTSHRCA1
SCHEMBL10893311 0.88 LMNA (0.42) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL28309093 0.88 LMNA (0.42) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL28104507 0.88 LMNA (0.42) LPAR3LPAR2THRBTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1958980-B1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORP (JP) 2012-10-31 EP disclosed
US-20090270525-A1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORPORATION (JP) 2009-10-29 US disclosed
EP-1958980-A1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR Corporation (JP) 2008-08-20 EP disclosed
US-6838538-B2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2005-01-04 US disclosed
US-20030100683-A1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2003-05-29 US disclosed
EP-1245585-A2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR Corporation (JP) 2002-10-02 EP disclosed
EP-0646672-B1 Coated fabrics for air bags WACKER CHEMIE GMBH (DE) 1996-11-06 EP disclosed
EP-0582972-B1 Detergent resistant compositions WACKER CHEMIE GMBH (DE) 1995-10-25 EP disclosed
EP-0646672-A1 Coated fabrics for air bags Wacker-Chemie GmbH (DE) 1995-04-05 EP disclosed
US-5401566-A Polysiloxane coating WACKER SILICONES CORPORATION (US) 1995-03-28 US disclosed
EP-0582972-A2 Detergent resistant compositions Wacker-Chemie GmbH (DE) 1994-02-16 EP disclosed
US-5264027-A Polysiloxanes WACKER SILICONES CORPORATION (US) 1993-11-23 US disclosed