SCHEMBL826100

SCHEMBL826100

CCCCCCCCCCCCCCCCO[Si](CC)(OCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 6/20 0.43
LPAR2 Q9HBW0 5/20 0.43
THRB P10828 2/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.39
CA1 P00915 8/20 0.38
CA2 P00918 8/20 0.38
CA9 Q16790 7/20 0.38
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
LPAR1 Q92633 2/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454270 1.00 LPAR3 (0.43) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL1609029 0.97 LPAR3 (0.39) LPAR3LPAR2THRBTSHRMEN1
Methylamine SCHEMBL2763140 0.95 CA1 (0.40) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL27876576 0.93 LPAR3 (0.39) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL1494567 0.93 LPAR3 (0.39) LPAR3LPAR2THRBTSHRMEN1
Fluoride SCHEMBL28795057 0.91 LPAR3 (0.38) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL150402 0.89 ADRB2 (0.41) LPAR3LPAR2THRBTSHRCA1
SCHEMBL10893311 0.88 LMNA (0.42) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL28309093 0.88 LMNA (0.42) LPAR3LPAR2THRBTSHRMEN1
SCHEMBL28104507 0.88 LMNA (0.42) LPAR3LPAR2THRBTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1957597-B1 CONTINUOUS PROCESS FOR PRODUCTION OF SILICONE PRESSURE SENSITIVE ADHESIVES DOW CORNING (US) 2014-04-30 EP disclosed
US-8298367-B2 Pressure sensitive adhesives and methods for their preparation DOW CORNING CORPORATION (US) 2012-10-30 US disclosed
EP-1904597-B1 PRESSURE SENSITIVE ADHESIVES AND METHODS FOR THEIR PREPARATION DOW CORNING (US) 2012-08-22 EP disclosed
US-8141324-B2 Structural attachment media DOW CORNING CORPORATION (US) 2012-03-27 US disclosed
US-20090294023-A1 Pressure sensitive adhesives and methods for their preparation DOW CORNING CORPORATION 2009-12-03 US disclosed
US-20090077921-A1 Structural attachment media DOW SILICONES CORPORATION 2009-03-26 US disclosed
US-20080300358-A1 Continuous Process For Production Of Silicone Pressure Sensitive Adhesives DOW CORNING CORPORATION 2008-12-04 US disclosed
EP-1957597-A2 CONTINUOUS PROCESS FOR PRODUCTION OF SILICONE PRESSURE SENSITIVE ADHESIVES Dow Corning Corporation (US) 2008-08-20 EP disclosed
EP-1904597-A2 PRESSURE SENSITIVE ADHESIVES AND METHODS FOR THEIR PREPARATION Dow Corning Corporation (US) 2008-04-02 EP disclosed
EP-1904709-A1 STRUCTURAL ATTACHMENT MEDIA Dow Corning Corporation (US) 2008-04-02 EP disclosed
WO-2007067332-A2 CONTINUOUS PROCESS FOR PRODUCTION OF SILICONE PRESSURE SENSITIVE ADHESIVES DOW CORNING CORPORATION (US) 2007-06-14 WO disclosed
WO-2007011538-A2 PRESSURE SENSITIVE ADHESIVES AND METHODS FOR THEIR PREPARATION DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed
WO-2007011540-A1 STRUCTURAL ATTACHMENT MEDIA DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed
EP-0980871-A2 Process for preparing acetoxy silanes Degussa-Hüls Aktiengesellschaft (DE) 2000-02-23 EP disclosed