SCHEMBL4453597

SCHEMBL4453597

Clc1cc(Cl)cc(-c2c(Cl)cc(Cl)cc2Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.68
TSHR P16473 7/20 0.53
ALDH1A1 P00352 6/20 0.50
CYP3A4 P08684 5/20 0.45
HSD17B10 Q99714 5/20 0.45
RECQL P46063 3/20 0.45
TP53 P04637 3/20 0.40
HPGD P15428 3/20 0.39
CES1 P23141 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 2/20 0.35
ALOX12 P18054 2/20 0.35
MAPK1 P28482 2/20 0.35
CASP1 P29466 2/20 0.35
CASP7 P55210 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459925 0.81 AHR (1.00) AHRTSHRALDH1A1CYP3A4HSD17B10
SCHEMBL4448776 0.79 AHR (0.46) AHRTSHRALDH1A1CES1RXRA
SCHEMBL2937097 0.78 TSHR (0.67) AHRTSHRALDH1A1CYP3A4HSD17B10
SCHEMBL463754 0.78 TSHR (0.73) AHRTSHRALDH1A1CYP3A4HSD17B10
SCHEMBL15413052 0.77 AHR (0.56) AHRTSHRALDH1A1CYP3A4HSD17B10
SCHEMBL4449545 0.77 AHR (0.56) AHRTSHRALDH1A1CYP3A4HSD17B10
SCHEMBL2936537 0.75 AHR (0.55) AHRTSHRALDH1A1CYP3A4HSD17B10
SCHEMBL4454430 0.75 AHR (0.55) AHRTSHRALDH1A1CYP3A4HSD17B10
SCHEMBL1046307 0.75 AHR (0.54) AHRALDH1A1HSD17B10HPGDSMN1; SMN2
SCHEMBL4458179 0.75 ALOX5 (0.48) AHRTSHRALDH1A1TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4160211-A1 DETECTING THE EXPOSURE OF A SUBJECT TO A THYROID DISRUPTING CHEMICAL, EVEN BEFORE HYPOTHYROIDISM APPEARS Moreno Navarro, José Carlos (ES) 2023-04-05 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
WO-2025044554-A1 SEPARABLE SKIN PARAMETER MEASUREMENT MODULE 北京他山科技有限公司 2025-03-06 WO disclosed
CN-116632385-B Battery Pack 蜂巢能源科技股份有限公司 2025-02-25 CN disclosed
CN-222298717-U Chassis position sensor and damper 大陆汽车安全系统(长春)有限公司 2025-01-03 CN disclosed
CN-111816997-B Antenna module and electronic device comprising same 三星电子株式会社 2024-12-17 CN disclosed
CN-110107214-B Photosensitive element assembly 路创电子公司 2024-10-01 CN disclosed
CN-113841008-B Intelligent candle platform and system 卢德拉技术有限责任公司 2024-08-20 CN disclosed
CN-221552103-U Battery mounting structure and electronic equipment 欣旺达电子股份有限公司 2024-08-16 CN disclosed
CN-221285708-U Split type skin parameter detection module 北京他山科技有限公司 2024-07-09 CN disclosed
CN-114253363-B Multi-node server, cabinet server and blade server 华为技术有限公司 2024-04-09 CN disclosed
CN-217407537-U Scalable folding electric mosquito swatter 惠州市博美电源科技有限公司 2022-09-13 CN disclosed
CN-114563304-B Snow density in-situ detection sensor 中国气象科学研究院 2022-07-15 CN disclosed
CN-114563304-A Snow density in-situ detection sensor 中国气象科学研究院 2022-05-31 CN disclosed
WO-2022062926-A1 MULTI-NODE SERVER, CABINET SERVER AND BLADE SERVER 华为技术有限公司 2022-03-31 WO disclosed
CN-114253363-A Multi-node server, cabinet type server and blade type server 华为技术有限公司 2022-03-29 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed