Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.67 |
| ▸ | CCR5 | P51681 | 1/20 | 0.56 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.56 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2697037 | 0.99 | CCR2 (0.66) | CCR2CCR5CXCR5CXCR3ALDH1A1 | |
| Iodide SCHEMBL17555074 | 0.99 | CCR2 (0.66) | CCR2CCR5CXCR5CXCR3ALDH1A1 | |
| SCHEMBL13148348 | 0.91 | ALDH1A1 (0.57) | CCR2CXCR5CXCR3ALDH1A1MAPT | |
| SCHEMBL2695793 | 0.89 | CCR2 (0.56) | CCR2CCR5CXCR5CXCR3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2907820 | 0.88 | CCR2 (0.55) | CCR2CCR5CXCR5CXCR3ALDH1A1 | |
| Iodide SCHEMBL17555122 | 0.88 | CCR2 (0.55) | CCR2CCR5CXCR5CXCR3ALDH1A1 | |
| SCHEMBL13148261 | 0.81 | CCR2 (0.87) | CCR2CCR5CXCR5CXCR3 | |
| SCHEMBL3076805 | 0.81 | CCR2 (1.00) | CCR2CCR5CXCR5CXCR3 | |
| Iodide SCHEMBL17555130 | 0.80 | CCR2 (0.85) | CCR2CCR5CXCR5CXCR3 | |
| Hydrochloric Acid SCHEMBL2907826 | 0.80 | CCR2 (0.85) | CCR2CCR5CXCR5CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090112003-A1 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090112003-A1 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS | CCR2, CCR1, CCL11 | CCR2 1/4885CCR5 7/4885CXCR5 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.