Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL5713246 | 0.89 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL589610 | 0.87 | — | — | |
| SCHEMBL4451044 | 0.76 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL10514272 | 0.70 | — | — | |
| Cyclohexane SCHEMBL4451045 | 0.66 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4041684 | 0.65 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL2828421 | 0.65 | — | — | |
| SCHEMBL29082783 | 0.62 | — | — | |
| SCHEMBL2830204 | 0.61 | — | — | |
| SCHEMBL6692899 | 0.60 | KMT2A (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735438-B | Guanidino-containing catalysts | SIKA技术股份公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-107253944-B | Tetrahydro benzo thiophene derivant and its preparing the purposes in glycogen synthase kinase 3-beta inhibitors | 哈尔滨医科大学 | 2019-11-22 | — | — | CN | disclosed |
| CN-107735438-A | Catalyst containing guanidine radicals | SIKA技术股份公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-107253944-A | Tetrahydro benzo thiophene derivant and its purposes in glycogen synthase kinase 3-beta inhibitors are prepared | 哈尔滨医科大学 | 2017-10-17 | — | — | CN | disclosed |
| EP-1732543-B1 | TETRACYCLIC CARBOLINE DERATIVES FOR INHIBITING ANGIOGENESIS | PTC THERAPEUTICS INC (US) | 2017-05-10 | — | — | EP | disclosed |
| US-8940896-B2 | Tetra-cyclic carboline derivatives useful in the inhibition of angiogenesis | PTC THERAPEUTICS, INC. (US) | 2015-01-27 | — | — | US | disclosed |
| EP-1524289-B1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-20080182866-A1 | Tetra-Cyclic Carboline Derivatives Useful in the Inhibition of Angiogenesis | PTC THERAPEUTICS , INC. A CORPORATION | 2008-07-31 | — | — | US | disclosed |
| US-20070149639-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | HORIKOSHI HIROSHI | 2007-06-28 | — | — | US | disclosed |
| EP-1732543-A2 | TETRA-CYCLIC CARBOLINE DERATIVES FOR INHIBITING ANGIOGENESIS | PTC Therapeutics, Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| US-7070840-B2 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| WO-2005089752-A2 | TETRA-CYCLIC CARBOLINE DERIVATIVES FOR INHIBITING ANGIOGENESIS | PTC THERAPEUTICS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| EP-1524289-A1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | TANABE SEIYAKU CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1373247-A2 | SPIROISOQUINOLINE COMPOUNDS, METHODS FOR THEIR PREPARATION AND INTERMEDIATES THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-20030068476-A1 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. | 2003-04-10 | — | — | US | disclosed |
| EP-1253021-A2 | Inkjet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-30 | — | — | EP | disclosed |
| WO-2002079189-A2 | SPIROISOQUINOLINE COMPOUNDS, METHODS FOR THEIR PREPARATION AND INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 2002-10-10 | — | — | WO | disclosed |
| US-4656217-A | CURABLE CARBOXY-CONTAINING POLYMER MODIFIED BY AN UNSATURATED AZIRIDINE COMPOUND; ADHESIVES, CONCRETE SLABS; CASTINGS | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1987-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | KCNN1, KCNN2, KCNN3 | ALDH1A1 1229/4885 |
| US-20080182866-A1 | Tetra-Cyclic Carboline Derivatives Useful in the Inhibition of Angiogenesis | VEGFA, TEK, FLT4 | ALDH1A1 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.