SCHEMBL4454747

SCHEMBL4454747

CCNS(=O)(=O)c1ccc(F)c(OC)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
LMNA P02545 3/20 0.59
HTT P42858 3/20 0.57
GAA P10253 1/20 0.57
HPGD P15428 1/20 0.57
KDM4E B2RXH2 2/20 0.56
POLB P06746 1/20 0.54
KMT2A Q03164 3/20 0.53
MAPK1 P28482 1/20 0.52
MEP1B Q16820 1/20 0.52
TSHR P16473 2/20 0.49
MEN1 O00255 1/20 0.49
PKM P14618 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
PDE4A P27815 1/20 0.49
PDE4B Q07343 1/20 0.49
PDE4C Q08493 1/20 0.49
PDE4D Q08499 1/20 0.49
GLA P06280 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4609361 0.85 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2LMNAHTTPOLB
SCHEMBL10154347 0.82 LMNA (0.64) ALDH1A1SMN1; SMN2LMNAHTTGAA
SCHEMBL29651875 0.78 LMNA (0.55) ALDH1A1SMN1; SMN2LMNAHTTGAA
SCHEMBL1816396 0.78 LMNA (0.55) ALDH1A1SMN1; SMN2LMNAHTTGAA
SCHEMBL24429355 0.78 SMN1; SMN2 (0.60) ALDH1A1SMN1; SMN2LMNAHTTGAA
SCHEMBL20155326 0.78 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2POLBKMT2APKM
SCHEMBL17101814 0.76 SMN1; SMN2 (0.72) ALDH1A1SMN1; SMN2LMNAHTTGAA
SCHEMBL13211247 0.76 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2LMNAHTTGAA
SCHEMBL27459443 0.75 PTGS2 (0.55) ALDH1A1SMN1; SMN2LMNAHTTGAA
SCHEMBL11460936 0.75 MAPK1 (0.69) ALDH1A1SMN1; SMN2LMNAHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114163-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-11-11 EP claimed
WO-2008125410-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2008-10-23 WO claimed
EP-3152189-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO Dow AgroSciences LLC (US) 2017-04-12 EP disclosed
EP-3071036-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS Dow AgroSciences LLC (US) 2016-09-28 EP disclosed
WO-2015191430-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2015-12-17 WO disclosed
WO-2015061165-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2015-04-30 WO disclosed