SCHEMBL4181918

SCHEMBL4181918

O=P(O)(O)OP(=O)(O)OP(=O)(O)Oc1cc(O)cc(O)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 7/20 0.45
INPP5A Q14642 4/20 0.45
INPP5B P32019 1/20 0.35
FDPS P14324 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SRC P12931 3/20 0.33
BACE1 P56817 2/20 0.32
HSP90AA1 P07900 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4179021 0.96 INPPL1 (0.48) INPPL1INPP5AINPP5BFDPSBLM
Triphosphate SCHEMBL4186099 0.85 FDPS (0.45) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL3997816 0.80 CA2 (0.47) INPPL1INPP5ABLMTDP1SRC
SCHEMBL4186090 0.79 TDP1 (0.38) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL4454764 0.79 INPPL1 (0.71) INPPL1INPP5AINPP5BBLMSRC
SCHEMBL130698 0.78 SRC (0.49) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL30381194 0.78 SRC (0.49) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL2763623 0.77 PTGS2 (0.54) BLMTDP1KDM4EMEN1KMT2A
Phosphoric Acid SCHEMBL8852885 0.77 SRC (0.47) INPPL1INPP5AINPP5BSRCKDM4E
Pyrophosphoric Acid SCHEMBL4179033 0.76 FDPS (0.59) INPPL1INPP5AINPP5BFDPSBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US claimed
JP-2008545385-A 2008-12-18 JP claimed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP claimed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO claimed
CN-117222705-A Thermosetting composition, method for producing molded article using same, and cured article 出光兴产株式会社 2023-12-12 CN disclosed
CN-117178003-A Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article 出光兴产株式会社 2023-12-05 CN disclosed
CN-117120494-A Thermosetting composition, method for producing molded article using same, and cured article 出光兴产株式会社 2023-11-24 CN disclosed
CN-117098787-A Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article 出光兴产株式会社 2023-11-21 CN disclosed
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP disclosed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098589-A1 Method ALPL, PPA1, ITPA INPPL1 40/4885INPP5A 15/4885INPP5B 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.