Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741182 | 0.95 | CNR1 (0.43) | NCEH1GAATDP1L3MBTL1KDM4E | |
| SCHEMBL9518357 | 0.94 | CNR1 (0.44) | NCEH1GAAKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL29497324 | 0.90 | KDM4E (0.49) | NCEH1GAATDP1L3MBTL1KDM4E | |
| SCHEMBL4525808 | 0.90 | KDM4E (0.49) | NCEH1GAATDP1L3MBTL1KDM4E | |
| SCHEMBL2098305 | 0.83 | NCEH1 (0.42) | NCEH1GAATDP1KDM4EHSD17B10 | |
| SCHEMBL8741111 | 0.81 | MAPT (0.41) | CNR1TLR8 | |
| SCHEMBL9310442 | 0.79 | KMT2A (0.35) | NCEH1GAATDP1KDM4EHSD17B10 | |
| SCHEMBL9485440 | 0.78 | GAA (0.47) | NCEH1GAATDP1L3MBTL1KDM4E | |
| SCHEMBL2846325 | 0.78 | NCEH1 (0.52) | NCEH1GAATDP1L3MBTL1KDM4E | |
| SCHEMBL10426036 | 0.77 | THRA (0.37) | TDP1KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716409-B2 | Carboxylate terminated polymers and their use in impact-modified plastics | FIRESTONE POLYMERS, LLC (US) | 2014-05-06 | — | — | US | claimed |
| US-20080161448-A1 | Carboxylate Terminated Polymers and Their Use in Impact-Modified Plastics | FIRESTONE POLYMERS, LLC | 2008-07-03 | — | — | US | claimed |
| EP-1373323-B1 | CO2-TERMINATED RUBBER | FIRESTONE POLYMERS LLC (US) | 2007-02-28 | — | — | EP | claimed |
| US-7105613-B2 | CO2 terminated rubber for plastics | FIRESTONE POLYMERS, LLC (US) | 2006-09-12 | — | — | US | claimed |
| US-20050131153-A1 | CO2 terminated rubber for plastics | LION ELASTOMERS ORANGE, LLC | 2005-06-16 | — | — | US | claimed |
| US-6881795-B2 | CO2 terminated rubber for plastics | FIRESTONE POLYMERS, LLC (US) | 2005-04-19 | — | — | US | claimed |
| US-20020183468-A1 | CO2 terminated rubber for plastics | LION ELASTOMERS ORANGE, LLC | 2002-12-05 | — | — | US | claimed |
| EP-2111420-B1 | CARBOXYLATE TERMINATED POLYMERS AND THEIR USE IN IMPACT-MODIFIED PLASTICS | BRIDGESTONE CORP (JP) | 2017-05-31 | — | — | EP | disclosed |
| CN-101657475-B | Carboxylate terminated polymer and the purposes in impact-modified plastics thereof | BRIDGESTONE CO.,LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |
| US-8716409-B2 | Carboxylate terminated polymers and their use in impact-modified plastics | FIRESTONE POLYMERS, LLC (US) | 2014-05-06 | — | — | US | disclosed |
| CN-101657475-A | Carboxylate terminated polymers and their use in impact-modified plastics | BRIDGESTONE CORP US | 2010-02-24 | — | — | CN | disclosed |
| EP-2111420-A1 | CARBOXYLATE TERMINATED POLYMERS AND THEIR USE IN IMPACT-MODIFIED PLASTICS | Bridgestone Corporation (JP) | 2009-10-28 | — | — | EP | disclosed |
| WO-2008100309-A1 | CARBOXYLATE TERMINATED POLYMERS AND THEIR USE IN IMPACT-MODIFIED PLASTICS | BRIDGESTONE CORPORATION (JP) | 2008-08-21 | — | — | WO | disclosed |
| US-4264753-A | USING AN ORGANO LITHIUM AND DIHETEROCYCLIC BRIDGED AMINE AS CATALYST SYSTEM | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4247418-A | ORGANO-LITHIUM COMPOUND WITH A BICYCLIC AMINE | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-01-27 | — | — | US | disclosed |
| US-4174431-A | CATALYST COMPRISING DIHYDROCARBYL MAGNESIUM AND ORGANIC ALKALI METAL COMPOUND | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4148984-A | TRIALKYLALUMINUM WITH ALKALI METAL COMPOUNDS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4139490-A | HIGH MOLECULAR WEIGHT POLYBUTADIENE | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
| US-4107081-A | TRIHYDROCARBYLALUMINUM COMPOUNDS WITH ALKALI METAL COMPOUNDS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-3953542-A | CATALYST OF VANADIUM OR TITANIUM HALIDE, ALUMINUM TRIHYDROCARBON, AND A CARBONYL COMPOUND | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161448-A1 | Carboxylate Terminated Polymers and Their Use in Impact-Modified Plastics | ZYX, LPO, ALOX5 | NCEH1 1863/4885GAA 2541/4885TDP1 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.