Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.52 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31054290 | 0.89 | KDM1A (0.53) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL29111427 | 0.79 | KDM1A (0.46) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL30444472 | 0.78 | ALDH1A1 (0.60) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL1962849 | 0.78 | ALDH1A1 (0.60) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL4223320 | 0.77 | HTR1A (0.46) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL2877816 | 0.77 | KDM1A (0.54) | KDM1AMAOAMAOBRCOR1KDM1B | |
| Hydrochloric Acid SCHEMBL29111428 | 0.77 | KDM1A (0.46) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL12362785 | 0.76 | KDM1A (0.46) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL30669238 | 0.76 | HSD11B1 (0.55) | MAOAMAOBMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10191867 | 0.76 | HSD11B1 (0.55) | MAOAMAOBMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |