SCHEMBL4455460

SCHEMBL4455460

CCc1cccc(OP(=O)(Oc2cccc(CC)c2CC)c2ccccc2)c1CC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTT P42858 1/20 0.44
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA4 P22748 3/20 0.37
CA5A P35218 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 3/20 0.37
CA5B Q9Y2D0 3/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HIF1A Q16665 1/20 0.36
CFTR P13569 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779558 0.86 L3MBTL1 (0.52) L3MBTL1TDP1HTTMEN1KMT2A
SCHEMBL4455464 0.84 HTT (0.42) L3MBTL1HTTMEN1KMT2ACA12
SCHEMBL4458097 0.84 L3MBTL1 (0.37) L3MBTL1HTTMEN1KMT2AMAPT
SCHEMBL4456014 0.83 LTB4R (0.43) L3MBTL1TDP1HTTMEN1KMT2A
SCHEMBL11125084 0.81 HTT (0.39) L3MBTL1HTTMEN1KMT2AMAPT
SCHEMBL761161 0.81 GABRA1 (0.39) L3MBTL1HTTMAPTNPSR1
SCHEMBL4446208 0.81 GABRA1 (0.39) L3MBTL1HTTMAPTNPSR1
SCHEMBL4462327 0.81 LTB4R (0.42) L3MBTL1TDP1HTTMEN1KMT2A
SCHEMBL28173346 0.81 L3MBTL1 (0.65) L3MBTL1TDP1HTTMEN1KMT2A
SCHEMBL4454061 0.80 MAPT (0.37) L3MBTL1HTTMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed
EP-0013744-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT Standard Oil Company (US) 1984-11-07 EP disclosed
US-4233182-A High activity catalyst for the polymerization of alpha-olefins STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
US-4233253-A Method for the preparation of metal salts of phosphorus acid esters STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
EP-0013744-A1 Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component Standard Oil Company (US) 1980-08-06 EP disclosed