Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114683 | 0.84 | EPHX1 (0.46) | EPHX1TRPM8TRPA1TRPV1CYP19A1 | |
| SCHEMBL29450387 | 0.79 | EPHX1 (0.44) | EPHX1TRPM8TRPA1TRPV1CYP19A1 | |
| SCHEMBL4594644 | 0.79 | EPHX1 (0.44) | EPHX1TRPM8TRPA1TRPV1CYP19A1 | |
| SCHEMBL11291061 | 0.78 | EPHX1 (0.49) | EPHX1TRPM8TRPA1TRPV1CYP19A1 | |
| SCHEMBL15917452 | 0.77 | TRPM8 (0.43) | EPHX1TRPM8TRPA1TRPV1CYP19A1 | |
| SCHEMBL16684822 | 0.77 | EPHX1 (0.43) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL21350192 | 0.77 | MEN1 (0.46) | TRPM8TRPV1CYP19A1ALDH1A1HPGD | |
| SCHEMBL19020350 | 0.77 | CYP19A1 (0.53) | TRPM8CYP19A1ALDH1A1HPGD | |
| SCHEMBL9951572 | 0.77 | EPHX1 (0.51) | EPHX1TRPM8TRPA1TRPV1CYP19A1 | |
| SCHEMBL457824 | 0.77 | EPHX1 (0.51) | EPHX1TRPM8TRPA1TRPV1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033688-B1 | Oxalic acid derivatives and their use as physiological cooling agents | SYMRISE AG (DE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2033688-A2 | Oxalic acid derivatives and their use as physiological cooling agents | Symrise GmbH & Co. KG (DE) | 2009-03-11 | — | — | EP | disclosed |