SCHEMBL114683

SCHEMBL114683

CC(=O)OCC1CC(C)CCC1C(C)C

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.46
TRPM8 Q7Z2W7 4/20 0.46
TRPA1 O75762 2/20 0.44
CYP19A1 P11511 2/20 0.39
ALDH1A1 P00352 4/20 0.38
HPGD P15428 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
MAPT P10636 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114684 0.84 EPHX1 (0.44) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL4455481 0.84 EPHX1 (0.44) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL15917452 0.83 TRPM8 (0.43) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL28350744 0.80 EPHX1 (0.51) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL9996875 0.79 EPHX1 (0.45) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL113449 0.79 TRPM8 (0.48) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL4594644 0.78 EPHX1 (0.44) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL29450387 0.78 EPHX1 (0.44) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL10028627 0.78 EPHX1 (0.59) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
Acetic Acid SCHEMBL30541669 0.77 EPHX1 (0.49) EPHX1TRPM8TRPA1CYP19A1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140348756-A1 WATER-FREE FORMULATIONS HAVING A COOLING EFFECT HENKEL AG & CO. KGAA (DE) 2014-11-27 US claimed
US-12128257-B2 Extracts of Isochrysis sp SYMRISE AG (DE) 2024-10-29 US disclosed
CN-117355218-A Flavor beads and methods of making and using the same 威·曼父子有限公司 2024-01-05 CN disclosed
CN-116546890-A Liquid composition comprising cereal beta-glucan or cereal extract containing beta-glucan 西姆莱斯股份公司 2023-08-04 CN disclosed
CN-113543637-B Antimicrobial mixture 西姆莱斯股份公司 2023-07-14 CN disclosed
CN-113766911-A Plant peptides and uses thereof (II) 西姆莱斯股份公司 2021-12-07 CN disclosed
EP-3348255-B1 EXTRACTS OF TETRASELMIS SP. FOR COSMETIC AND THERAPEUTIC PURPOSES SYMRISE AG (DE) 2021-11-10 EP disclosed
US-20200222730-A1 Extracts of Isochrysis sp. SYMRISE AG (DE) 2020-07-16 US disclosed
CN-107410304-B Compositions comprising benzyl alcohol derivatives and other antimicrobially active compounds 西姆莱斯有限公司 2020-06-12 CN disclosed
US-10463891-B2 Extracts of Isochrysis sp. SYMRISE AG (DE) 2019-11-05 US disclosed
EP-2424829-A2 OMEGA-CYCLOHEXYLALKAN-1-OLES AND USE THEREOF AS ANTIMICROBIAL ACTIVES TO COMBAT BODY ODOR Symrise AG (DE) 2012-03-07 EP disclosed
EP-2306820-A2 COMPOSITIONS COMPRISING BENZYL ALCOHOL DERIVATIVES AND FURTHER ANTIMICROBIAL ACTIVE COMPOUNDS Symrise AG (DE) 2011-04-13 EP disclosed
US-20100143267-A1 EXTRACTS OF TETRASELMIS SP. SYMRISE GMBH & CO. KG (DE) 2010-06-10 US disclosed
EP-2193785-A2 Extracts of Tetraselmis sp. for cosmetic and therapeutic purposes Symrise GmbH & Co. KG (DE) 2010-06-09 EP disclosed
US-20100080761-A1 Extracts of Isochrysis sp. SYMRISE GMBH & CO. KG (DE) 2010-04-01 US disclosed
EP-2168570-A2 Extracts of isochrysis sp. Symrise GmbH & Co. KG (DE) 2010-03-31 EP disclosed
WO-2010000877-A2 FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL SYMRISE GMBH & CO. KG (DE) 2010-01-07 WO disclosed
WO-2009101216-A2 OMEGA-CYCLOHEXYLALKAN-1-OLES AND USE THEREOF AS ANTIMICROBIAL ACTIVES TO COMBAT BODY ODOR SYMRISE GMBH & CO. KG (DE) 2009-08-20 WO disclosed
US-20090123392-A1 FRAGRANCE ACCORDS TO COMBAT THE PERCEPTION OF BODY ODOR SYMRISE GMBH & CO. KG (DE) 2009-05-14 US disclosed
WO-2008119841-A2 COMPOSITIONS COMPRISING BENZYL ALCOHOL DERIVATIVES AND FURTHER ANTIMICROBIAL ACTIVE COMPOUNDS SYMRISE GMBH & CO. KG (DE) 2008-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140348756-A1 WATER-FREE FORMULATIONS HAVING A COOLING EFFECT CUTA, RDX, POLR1C EPHX1 673/4885TRPM8 3118/4885TRPA1 3427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.