⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903249 | 1.00 | — | — | |
| SCHEMBL8465359 | 0.84 | — | — | |
| SCHEMBL435511 | 0.84 | AKR1C3 (0.31) | — | |
| SCHEMBL31389031 | 0.83 | TSHR (0.36) | — | |
| SCHEMBL23455659 | 0.82 | — | — | |
| SCHEMBL403240 | 0.81 | CD81 (0.33) | — | |
| SCHEMBL1845478 | 0.79 | APEX1 (0.33) | — | |
| SCHEMBL1845476 | 0.79 | APEX1 (0.33) | — | |
| SCHEMBL809437 | 0.78 | TBXAS1 (0.33) | — | |
| SCHEMBL400292 | 0.78 | TBXAS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883152-A | HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER | NIPPON OIL AND FATS CO., LTD. (JP) | 1999-03-16 | — | — | US | claimed |
| EP-3756874-A2 | PINHOLE CONTACT LENS FORMING JIG | Seed Co., Ltd. (JP) | 2020-12-30 | — | — | EP | disclosed |
| EP-2650021-B1 | MEDICAL DEVICE FOR CONTROLLED RELEASE OF DRUG | SEED CO LTD (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-9056880-B2 | Process for producing hydrolysis-resistant silicone compounds | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-8969429-B2 | Low-tack, hydrophobic ophthalmic device materials | NOVARTIS AG (CH) | 2015-03-03 | — | — | US | disclosed |
| EP-2673666-B1 | LOW-TACK, HYDROPHOBIC OPHTHALMIC DEVICE MATERIALS | NOVARTIS AG (CH) | 2014-12-31 | — | — | EP | disclosed |
| US-8921449-B2 | Hydrolysis-resistant silicone compounds | JOHNSON & JOHNSON VISION CARE INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140128564-A1 | PROCESS FOR PRODUCING HYDROLYSIS-RESISTANT SILICONE COMPOUNDS | FUJISAWA KAZUHIKO (JP) | 2014-05-08 | — | — | US | disclosed |
| US-8662663-B2 | Hybrid soft contact lens, and production method and hydration treatment method thereof | MENICON CO., LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8637589-B2 | Silicone prepolymer solutions | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-20120202916-A1 | Low-Tack, Hydrophobic Ophthalmic Device Materials | NOVARTIS AG (CH) | 2012-08-09 | — | — | US | disclosed |
| US-20120065348-A1 | SOLUBLE SILICONE PREPOLYMERS | TORAY INDUSTRIES, INC. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-8080622-B2 | Soluble silicone prepolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-12-20 | — | — | US | disclosed |
| EP-2388281-A1 | SILICONE MONOMER | NOF Corporation (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20110282008-A1 | SILICONE MONOMER | NOF CORPORATION (JP) | 2011-11-17 | — | — | US | disclosed |
| US-8040078-B1 | LED dimming circuit | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2011-10-18 | — | — | US | disclosed |
| US-20110077322-A1 | Silicone Prepolymer Solutions | TORAY INDUSTRIES, INC. (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20090005528-A1 | SOLUBLE SILICONE PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-01-01 | — | — | US | disclosed |
| US-20080081850-A1 | Such as reaction of butyldimethylsilanol with 3-trichlorosilylpropyl methacrylate to produce 3-[tris(butyldimethylsiloxy)silyl]propyl methacrylate; steric hindrance, purity; copolymers with acrylate endcapped polysiloxane and acrylic monomers; contact and intraocular lenses, artificial cornea | JOHNSON & JOHNSON VISION CARE, INC. | 2008-04-03 | — | — | US | disclosed |
| US-7317117-B2 | Siloxanyl-containing monomers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-01-08 | — | — | US | disclosed |