SCHEMBL400292

SCHEMBL400292

CC(=CCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.33
CD81 P60033 1/20 0.32
PPARG P37231 1/20 0.31
EP300 Q09472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809437 1.00 TBXAS1 (0.33) TBXAS1CD81PPARGEP300
SCHEMBL1802297 0.94 TBXAS1 (0.31) TBXAS1
SCHEMBL8466019 0.92 TBXAS1 (0.32) TBXAS1CD81
SCHEMBL1803466 0.92 TBXAS1 (0.32) TBXAS1CD81
SCHEMBL2474722 0.90 TDP1 (0.33)
Acrylamide SCHEMBL17840598 0.90 ALDH1A1 (0.31)
SCHEMBL403240 0.89 CD81 (0.33) CD81PPARG
SCHEMBL1581278 0.86 TBXAS1 (0.33) TBXAS1CD81PPARGEP300
SCHEMBL442701 0.86 TBXAS1 (0.33) TBXAS1CD81PPARGEP300
SCHEMBL2783671 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828317-B1 HYDROPHILIC SILICONE MONOMERS, PROCESS FOR PREPARATION THEREOF AND THIN FILMS CONTAINING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2026-04-29 EP claimed
EP-3635450-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-05-08 EP claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20230285599-A1 BIOSENSING COMPOSITION HAVING SENSING GLUCOSE CONTENT, CONTACT LENS AND METHOD OF PREPARATION THEREOF NATIONAL YANG MING CHIAO TUNG UNIVERSITY (TW) 2023-09-14 US claimed
EP-3928967-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-26 EP claimed
EP-3802080-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-19 EP claimed
EP-3969268-B1 METHOD FOR PRODUCING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2023-07-05 EP claimed
EP-3824005-B1 LIQUID WOUND DRESSING COMPOSITION USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I (CZ) 2023-02-22 EP claimed
EP-3426717-B1 COMPOSITION COMPRISING ORGANOSILOXANE NANO LATEX AND PREPARATION OF ORGANOSILOXANE NANO LATEX MOMENTIVE PERFORMANCE MAT INC (US) 2021-10-20 EP claimed
EP-3634733-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2021-07-21 EP claimed
WO-2008116131-A2 PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS NOVARTIS AG (CH) 2008-09-25 WO claimed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP claimed
EP-0897399-B1 ACRYLIC POLYMER COMPOUNDS DU PONT (US) 2002-01-02 EP claimed
EP-0692100-B1 IMPROVED ITACONATE COPOLYMERIC COMPOSITIONS FOR CONTACT LENSES POLYMER TECHNOLOGY CORP (US) 1999-07-21 EP claimed
EP-0493320-B1 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA GEIGY AG (CH) 1996-07-31 EP claimed
EP-0406161-B1 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA GEIGY AG (CH) 1995-02-22 EP claimed
EP-0215817-B1 CONTINUOUS-WEAR LENSES Bausch & Lomb Incorporated (US) 1991-03-13 EP claimed
US-4829137-A Continuous-wear highly oxygen permeable contact lenses BAUSCH & LOMB INCORPORATED (US) 1989-05-09 US claimed
EP-0215817-A1 CONTINUOUS-WEAR LENSES. BAUSCH & LOMB (US) 1987-04-01 EP claimed
WO-1986004341-A1 CONTINUOUS-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed