Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465359 | 0.84 | — | — | |
| SCHEMBL445549 | 0.84 | — | — | |
| SCHEMBL11903249 | 0.84 | — | — | |
| SCHEMBL23455662 | 0.82 | — | — | |
| SCHEMBL442701 | 0.78 | TBXAS1 (0.33) | — | |
| SCHEMBL5852502 | 0.76 | HPGD (0.43) | AKR1C3 | |
| SCHEMBL399700 | 0.76 | HPGD (0.43) | AKR1C3 | |
| SCHEMBL403240 | 0.73 | CD81 (0.33) | — | |
| SCHEMBL402994 | 0.73 | CD81 (0.33) | — | |
| SCHEMBL25328727 | 0.72 | CD81 (0.31) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809344-B2 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2016-08-10 | — | — | EP | claimed |
| EP-2077292-B1 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN NEW CENTURY CORP (TW) | 2013-08-14 | — | — | EP | claimed |
| US-8101698-B2 | Surface active prepolymers with both fluorine-containing groups and hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2012-01-24 | — | — | US | claimed |
| US-8071704-B2 | Prepolymerizable surface active monomers with both fluorine-containing groups and hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2011-12-06 | — | — | US | claimed |
| US-20110172374-A1 | NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH HEALTH HOLDCO LIMITED (IE) | 2011-07-14 | — | — | US | claimed |
| EP-2162474-B1 | NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB (US) | 2011-01-19 | — | — | EP | claimed |
| EP-2162474-A1 | NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE CONTAINING GROUPS AND HYDROPHILIC GROUPS | Bausch & Lomb Incorporated (US) | 2010-03-17 | — | — | EP | claimed |
| EP-1809344-B1 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2010-01-20 | — | — | EP | claimed |
| US-20090092655-A1 | NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) | 2009-04-09 | — | — | US | claimed |
| WO-2009045886-A1 | NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2009-04-09 | — | — | WO | claimed |
| EP-0611367-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | claimed |
| EP-0603268-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS. | BAUSCH & LOMB (US) | 1994-06-29 | — | — | EP | claimed |
| EP-0603270-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR MAKING THEM | BAUSCH & LOMB INCORPORATED (US) | 1994-06-29 | — | — | EP | claimed |
| WO-1993009154-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | claimed |
| WO-1993009155-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | claimed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | claimed |
| WO-1993005085-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS | BAUSCH & LOMB INCORPORATED (US) | 1993-03-18 | — | — | WO | claimed |
| WO-1993005098-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS | BAUSCH & LOMB INCORPORATED (US) | 1993-03-18 | — | — | WO | claimed |
| US-5100992-A | Chain extended with a dicarboxylic acid, block and graft polymers, medical applications, drug delivery | BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) | 1992-03-31 | — | — | US | claimed |
| EP-0396429-A2 | Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same | BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) | 1990-11-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092655-A1 | NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | NOTUM, ITK, MFAP1 | AKR1C3 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.