Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.80 |
| ▸ | PGR | P06401 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | MMP1 | P03956 | 15/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 1/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156674 | 0.99 | NR3C1 (0.81) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11152776 | 0.97 | NR3C1 (0.82) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11162374 | 0.94 | NR3C1 (0.79) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11433058 | 0.93 | NR3C1 (0.74) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11424740 | 0.92 | NR3C1 (0.73) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL7205322 | 0.92 | NR3C1 (0.69) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11421450 | 0.91 | NR3C1 (0.72) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL7595137 | 0.91 | NR3C1 (0.80) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11422072 | 0.91 | NR3C1 (0.82) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11439432 | 0.91 | NR3C1 (0.71) | NR3C1PGRMEN1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710036-B2 | Carbonate and carbamate modified forms of glucocorticoids in combination with β2 adrenergic agonists | SUNOVION PHARMACEUTICALS INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130244988-A1 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS | SUNOVION PHARMACEUTICALS INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-8445470-B2 | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists | SUNOVION PHARMACEUTICALS INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20090163456-A1 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS | SEPRACOR INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-7468362-B2 | Carbonate and carbamate modified forms of glucocorticoids in combination with β2 adrenergic agonists | SEPRACOR INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080103119-A1 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS | SEPRACOR INC. (US) | 2008-05-01 | — | — | US | disclosed |
| US-7253156-B2 | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists | SEPRACOR INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-20060148775-A1 | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists | SEPRACOR INC. (US) | 2006-07-06 | — | — | US | disclosed |
| US-7018995-B2 | Carbonate and carbamate modified forms of glucocorticoids | SEPRACOR INC. (US) | 2006-03-28 | — | — | US | disclosed |
| US-20050009798-A1 | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists | SEPRACOR INC. (US) | 2005-01-13 | — | — | US | disclosed |
| WO-2004047845-A1 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH β2 ADRENERGIC AGONISTS | SEPRACOR INC. (US) | 2004-06-10 | — | — | WO | disclosed |
| WO-2003070745-A2 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS | SEPRACOR INC. (US) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148775-A1 | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists | ADRB2, ADRA2C, NR3C2 | NR3C1 12/4885PGR 449/4885MEN1 1765/4885 |
| US-20080103119-A1 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS | ADRB2, ADRA2C, NR3C2 | NR3C1 12/4885PGR 449/4885MEN1 1765/4885 |
| US-20130244988-A1 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS | ADRB2, CHRM2, NR3C2 | NR3C1 10/4885PGR 443/4885MEN1 1963/4885 |
| US-20090163456-A1 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS | ADRB2, CHRM2, NR3C2 | NR3C1 10/4885PGR 443/4885MEN1 1963/4885 |
| US-20050009798-A1 | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists | ADRB2, ADRA2C, NR3C2 | NR3C1 12/4885PGR 449/4885MEN1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.