SCHEMBL445566

SCHEMBL445566

CC(=CCC(C)O)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30808136 1.00 TDP1 (0.31) TDP1LMNAALOX15BLMPMP22
SCHEMBL445565 1.00 TDP1 (0.31) TDP1LMNAALOX15BLMPMP22
Sulfuric Acid SCHEMBL3395417 0.92
Lactic Acid SCHEMBL339840 0.92 TP53 (0.42)
Acrylamide SCHEMBL21723571 0.90 ALDH1A1 (0.41) TDP1ALDH1A1
Methacrylic Acid SCHEMBL4418618 0.89 TDP1 (0.38) TDP1
SCHEMBL31482770 0.85
SCHEMBL3232685 0.84 GRIK1 (0.41) TDP1LMNAALOX15BLMPMP22
SCHEMBL630861 0.84 GRIK1 (0.41) TDP1LMNAALOX15BLMPMP22
SCHEMBL2047661 0.84 TDP1 (0.32) TDP1LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3837306-B1 FLUID FOR CONTROLLING THE PERMEABILITY OF A SUBTERRANEAN FORMATION, AND USE THEREOF ENI SPA (IT) 2026-05-06 EP claimed
US-12589182-B2 Occlusive implant compositions UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2026-03-31 US claimed
US-12570577-B2 Methods and compositions for inhibiting freeze-thaw damage in concrete and cement paste THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2026-03-10 US claimed
WO-2025260203-A1 CLICK CHEMISTRY POLYMER HYDROGELS ALLARTA LIFE SCIENCE INC. (CA) 2025-12-26 WO claimed
WO-2025260202-A1 AIR PRINTING OF HYDROGELS ALLARTA LIFE SCIENCE INC. (CA) 2025-12-26 WO claimed
WO-2025260204-A1 CROSSLINKED HYDROGELS WITH CONTROLLED PERMEABILITY ALLARTA LIFE SCIENCE INC. (CA) 2025-12-26 WO claimed
EP-4658250-A1 COMPOSITIONS AND METHODS BioNTech SE (DE) 2025-12-10 EP claimed
EP-4658249-A1 COMPOSITIONS AND METHODS BioNTech SE (DE) 2025-12-10 EP claimed
EP-4658248-A1 COMPOSITIONS AND METHODS BioNTech SE (DE) 2025-12-10 EP claimed
EP-4452643-B1 PROCESS FOR MANUFACTURING A MICROFLUIDIC DEVICE SURFIX B V (NL) 2025-11-26 EP claimed
US-20050070936-A1 Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2005-03-31 US claimed
US-6770219-B2 USING ACRYLATE OR ACRYLAMIDE POLYMERS NALCO ENERGY SERVICES 2004-08-03 US claimed
WO-2004035516-A1 COMPOSITION AND METHOD FOR PREVENTING FOULING IN (METH)ACRYLIC ACID PROCESSES NALCO ENERGY SERVICES, L.P. (US) 2004-04-29 WO claimed
US-20040072974-A1 COMPOSITION AND METHOD FOR PREVENTING FOULING IN (METH)ACRYLIC ACID PROCESSES ECOLAB USA INC. 2004-04-15 US claimed
US-20020173560-A1 Tire with component of rubber composition comprised of silica reinforcement and emulsion polymerization derived terpolymer rubber of diene/vinyl aromatic compound which contains pendant hydroxyl groups GOODYEAR TIRE & RUBBER COMPANY, THE 2002-11-21 US claimed
EP-1241204-A1 Tire with component of rubber composition comprised of silica reinforcement and emulsion polymerization derived terpolymer rubber of diene/vinyl aromatic compound which contains pendant hydroxyl groups THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-09-18 EP claimed
EP-0700295-A4 VITAMIN B 12? MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY LTD (AU) 1998-09-30 EP claimed
CN-1126441-A Amplification of vitamin B12 absorption System Using polymers BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
EP-0700295-A1 VITAMIN B 12? MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY. LIMITED (AU) 1996-03-13 EP claimed
WO-1994027613-A1 VITAMIN B12 MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY. LIMITED (AU) 1994-12-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570577-B2 Methods and compositions for inhibiting freeze-thaw damage in concrete and cement paste MTCL3, VCL, ATM TDP1 861/4885LMNA 319/4885ALOX15 4171/4885
US-12589182-B2 Occlusive implant compositions SHBG, NASP, TES TDP1 1973/4885LMNA 1615/4885ALOX15 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.