Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 11/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468813 | 1.00 | ACACB (0.50) | ACACBLDHAKDM6BPTPN1PPARA | |
| SCHEMBL18247995 | 0.85 | PTPN1 (0.55) | ACACBLDHAKDM6BPTPN1PPARA | |
| SCHEMBL20586417 | 0.85 | PTPN1 (0.55) | ACACBLDHAKDM6BPTPN1PPARA | |
| SCHEMBL4459826 | 0.84 | ACACB (0.51) | ACACBLDHAPPARAPPARGABCB1 | |
| SCHEMBL12040135 | 0.83 | ACACB (0.53) | ACACBLDHAPTPN1PPARAPPARG | |
| SCHEMBL2118353 | 0.82 | PTPN1 (0.68) | ACACBLDHAPTPN1PPARG | |
| SCHEMBL3497698 | 0.82 | ACACB (0.49) | ACACBLDHAPTPN1PPARAPPARG | |
| SCHEMBL1258519 | 0.82 | PTPN1 (0.68) | ACACBLDHAPTPN1PPARG | |
| SCHEMBL2867832 | 0.82 | PTPN1 (0.68) | ACACBLDHAPTPN1PPARG | |
| SCHEMBL8953524 | 0.81 | LDHA (0.73) | LDHAKDM6BPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1801224-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUENT-OXY-3-(4-SUBSTITUENT-OXYPHENYL)PROPIONIC ACID DERIVATIVE | Kaneka Corporation (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-4611002-A | Carboxymethyl esters of mercaptopropanoic acids as enkephalinase inhibitors | E. R. SQUIBB AND SONS, INC. (US) | 1986-09-09 | — | — | US | disclosed |
| US-4242265-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-12-30 | — | — | US | disclosed |