Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12040135 | 0.82 | ACACB (0.53) | ACACBLDHAPTPN1PPARAPPARG | |
| SCHEMBL4455664 | 0.82 | ACACB (0.50) | ACACBLDHAPTPN1PPARAPPARG | |
| SCHEMBL4468813 | 0.82 | ACACB (0.50) | ACACBLDHAPTPN1PPARAPPARG | |
| SCHEMBL5748284 | 0.81 | LDHA (0.71) | LDHAPPARAPPARG | |
| SCHEMBL1258519 | 0.81 | PTPN1 (0.68) | ACACBLDHAPTPN1PPARG | |
| SCHEMBL2118353 | 0.81 | PTPN1 (0.68) | ACACBLDHAPTPN1PPARG | |
| SCHEMBL2867832 | 0.81 | PTPN1 (0.68) | ACACBLDHAPTPN1PPARG | |
| SCHEMBL14728212 | 0.80 | LDHA (0.44) | LDHAPTPN1PPARAPPARG | |
| Hydrochloric Acid SCHEMBL2309162 | 0.79 | PTPN1 (0.67) | ACACBLDHAPTPN1 | |
| SCHEMBL4462336 | 0.79 | PPARA (0.57) | ACACBLDHAPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168443-A1 | Ethoid-Containing Compounds, Methods for Preparing Ethoid-Containing Compounds, and Methods of Use | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2008058016-A2 | ETHOID-CONTAINING COMPOUNDS, METHODS FOR PREPARING ETHOID-CONTAINING COMPOUNDS, AND METHODS FOR USE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168443-A1 | Ethoid-Containing Compounds, Methods for Preparing Ethoid-Containing Compounds, and Methods of Use | PARG, POLH, PHOSPHO1 | ACACB 2055/4885LDHA 2827/4885PTPN1 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.