Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302846 | 0.91 | LMNA (0.61) | LMNAPOLBJAK2ATMGRM5 | |
| SCHEMBL4447678 | 0.90 | LMNA (0.60) | LMNAPOLBJAK2KCNMA1GRM5 | |
| SCHEMBL13955088 | 0.90 | LMNA (0.51) | LMNAPOLBJAK2ATMNR3C1 | |
| SCHEMBL4445834 | 0.89 | LMNA (0.50) | LMNAPOLBATMMEN1KMT2A | |
| SCHEMBL4107917 | 0.89 | LMNA (0.64) | LMNAPOLBJAK2KCNMA1GRM5 | |
| SCHEMBL302426 | 0.89 | LMNA (0.64) | LMNAPOLBJAK2ATMGRM5 | |
| SCHEMBL13936356 | 0.88 | LMNA (0.56) | LMNAPOLBJAK2ATMHPGD | |
| SCHEMBL14578046 | 0.85 | LMNA (0.68) | LMNAPOLBATMNR3C1HTT | |
| SCHEMBL302989 | 0.85 | POLB (0.61) | LMNAPOLBATMNR3C1SMN1; SMN2 | |
| SCHEMBL303184 | 0.85 | LMNA (0.58) | LMNAPOLBJAK2JAK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | claimed |
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | disclosed |
| US-20090036509-A1 | N-(Ortho-Phenyl)-1-Methyl -3-Trifluoromethlpyrazole-4-Carboxanilides and Their Use as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-05 | — | — | US | disclosed |
| US-20090036509-A1 | N-(Ortho-Phenyl)-1-Methyl -3-Trifluoromethlpyrazole-4-Carboxanilides and Their Use as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | CBR3, CBR1, SNU13 | LMNA 3266/4885POLB 3502/4885JAK2 3286/4885 |
| US-20090036509-A1 | N-(Ortho-Phenyl)-1-Methyl -3-Trifluoromethlpyrazole-4-Carboxanilides and Their Use as Fungicides | CBR3, CBR1, DDT | LMNA 2270/4885POLB 3858/4885JAK2 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.