Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454040 | 0.84 | CA1 (0.42) | TDP1KCNH2TAAR1NPC1RAB9A | |
| SCHEMBL28524211 | 0.76 | LTA4H (0.53) | LTA4HTDP1L3MBTL1KCNH2TAAR1 | |
| SCHEMBL2355634 | 0.76 | LTA4H (0.75) | LTA4HTDP1L3MBTL1TAAR1MEN1 | |
| SCHEMBL27730422 | 0.73 | NPC1 (0.67) | LTA4HTDP1L3MBTL1KCNH2MEN1 | |
| SCHEMBL27615709 | 0.72 | TDP1 (0.77) | LTA4HTDP1L3MBTL1KCNH2TAAR1 | |
| SCHEMBL8338571 | 0.72 | TDP1 (0.77) | LTA4HTDP1L3MBTL1KCNH2TAAR1 | |
| SCHEMBL5632470 | 0.72 | LTA4H (0.69) | LTA4HTDP1L3MBTL1TAAR1NPC1 | |
| SCHEMBL3295781 | 0.72 | CA4 (0.54) | LTA4HTDP1L3MBTL1KMT2ANPC1 | |
| SCHEMBL31229726 | 0.72 | CA2 (0.41) | TDP1MEN1KMT2ACA4 | |
| SCHEMBL2846166 | 0.72 | TAAR1 (0.61) | LTA4HTDP1L3MBTL1TAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066601-A1 | HYDROSILYLATION | Agency for Science, Technology And Research (SG) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008039154-A1 | HYDROSILYLATION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-04-03 | — | — | WO | disclosed |