Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615709 | 1.00 | TDP1 (0.77) | TDP1L3MBTL1LTA4HABCB1MEN1 | |
| SCHEMBL8716189 | 0.95 | L3MBTL1 (0.70) | TDP1L3MBTL1LTA4HABCB1MEN1 | |
| SCHEMBL19210361 | 0.90 | L3MBTL1 (0.88) | TDP1L3MBTL1LTA4HABCB1MEN1 | |
| SCHEMBL12394563 | 0.88 | L3MBTL1 (0.97) | TDP1L3MBTL1LTA4HABCB1MEN1 | |
| SCHEMBL28551906 | 0.87 | LTA4H (0.69) | TDP1L3MBTL1LTA4HABCB1MEN1 | |
| SCHEMBL6429953 | 0.87 | LTA4H (0.69) | TDP1L3MBTL1LTA4HABCB1MEN1 | |
| SCHEMBL10468158 | 0.86 | CALM1 (0.68) | TDP1L3MBTL1LTA4HNPC1RAB9A | |
| SCHEMBL6208279 | 0.85 | NPC1 (0.62) | TDP1L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL1066576 | 0.84 | TSHR (0.67) | TDP1L3MBTL1LTA4HNPC1RAB9A | |
| SCHEMBL14327865 | 0.83 | MAOB (0.60) | TDP1L3MBTL1ABCB1BCHECHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998595-A | Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-07 | — | — | US | disclosed |