Biphenyl

Biphenyl

SCHEMBL4455977

CCCCOP.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.48
CYP2C9 P11712 3/20 0.43
CYP2C19 P33261 3/20 0.43
CYP2D6 P10635 3/20 0.43
CYP3A4 P08684 2/20 0.43
CYP19A1 P11511 2/20 0.43
LSS P48449 1/20 0.43
CYP1A2 P05177 2/20 0.42
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA4 P43681 1/20 0.41
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
PTPN1 P18031 1/20 0.40
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4459627 0.86 ALDH1A1 (0.43) LTA4HLSSL3MBTL1CHRNB2CHRNB4
Benzene SCHEMBL27705494 0.86 LTA4H (0.43) LTA4HCYP2C9CYP2C19CYP3A4CYP1A2
Biphenyl SCHEMBL15361769 0.82 LTA4H (0.52) LTA4HCYP2C9CYP2C19CYP2D6CYP3A4
Biphenyl SCHEMBL4462704 0.79 ALDH1A1 (0.50) LTA4HCYP3A4CYP1A2TDP1L3MBTL1
SCHEMBL9158869 0.78 LTA4H (0.70) LTA4HCYP2C9CYP2C19CYP2D6CYP3A4
Biphenyl SCHEMBL27538657 0.78 LTA4H (0.48) LTA4HCYP2C9CYP2C19CYP2D6CYP3A4
SCHEMBL5551477 0.78 LTA4H (0.70) LTA4HCYP2C9CYP2C19CYP2D6CYP3A4
Biphenyl SCHEMBL15347228 0.78 ALDH1A1 (0.56) LTA4HCYP2C9CYP2C19CYP2D6CYP1A2
Biphenyl SCHEMBL5868585 0.78 ALDH1A1 (0.56) LTA4HTSHRL3MBTL1ALDH1A1
SCHEMBL2230909 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102863559-B Photoinitiator for UV (ultraviolet)-LED curing NEWSUN CO LTD 2014-06-04 CN disclosed
CN-102863559-A Photoinitiator for UV (ultraviolet)-LED curing NEWSUN CO LTD 2013-01-09 CN disclosed
CN-101205268-B Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP 2010-09-29 CN disclosed
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
CN-101205268-A Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP (CN) 2008-06-25 CN disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed