Biphenyl

Biphenyl

SCHEMBL4459627

CCCOP.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HPGD P15428 2/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA7 P36544 1/20 0.39
CHRNA4 P43681 1/20 0.39
LTA4H P09960 2/20 0.38
MAPT P10636 1/20 0.38
LSS P48449 1/20 0.37
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
SLC6A4 P31645 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4455977 0.86 LTA4H (0.48) ALDH1A1L3MBTL1CHRNB2CHRNB4CHRNA3
Benzene SCHEMBL27705500 0.84 LMNA (0.34) ALDH1A1LMNAMEN1KMT2AHPGD
Biphenyl SCHEMBL4462704 0.82 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2L3MBTL1HPGDCHRNB2
Biphenyl SCHEMBL5146301 0.80 ALDH1A1 (0.47) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
Biphenyl SCHEMBL18140279 0.78 ALDH1A1 (0.45) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
Biphenyl SCHEMBL967556 0.76 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2L3MBTL1HPGDMAPT
SCHEMBL4450331 0.76
Biphenyl SCHEMBL11528031 0.74 ALDH1A1 (0.41) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
Biphenyl SCHEMBL843117 0.74 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2L3MBTL1HPGDMAPT
Biphenyl SCHEMBL4458119 0.73 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101205268-B Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP 2010-09-29 CN disclosed
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
CN-101205268-A Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP (CN) 2008-06-25 CN disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed