⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676087 | 0.72 | — | — | |
| SCHEMBL22400031 | 0.72 | — | — | |
| SCHEMBL15699484 | 0.67 | — | — | |
| SCHEMBL1931674 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL498964 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL22703581 | 0.65 | — | — | |
| SCHEMBL3738689 | 0.65 | — | — | |
| SCHEMBL721744 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL6570628 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL4257968 | 0.64 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328061-B2 | Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols | TRUSTEES OF BOSTON COLLEGE (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150057451-A1 | SIMPLE ORGANIC MOLECULES AS CATALYSTS FOR PRACTICAL AND EFFICIENT ENANTIOSELECTIVE SYNTHESIS OF AMINES AND ALCOHOLS | NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, U.S. GOVERNMENT | 2015-02-26 | — | — | US | disclosed |
| US-8263810-B2 | Stable borane reagents and methods for their use | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-09-11 | — | — | US | disclosed |
| US-20090088511-A1 | ELECTROLESS PLATING LIQUID | JSR CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20080287708-A1 | STABLE BORANE REAGENTS AND METHODS FOR THEIR USE | SIGMA-ALDRICH CO. NEWCO INC. | 2008-11-20 | — | — | US | disclosed |
| EP-1603557-A4 | SYNTHESIS OF PELORUSIDE A AND ANALOGS THEREOF FOR USE AS ANTITUMOR AGENTS | UNIV TEXAS (US) | 2008-05-21 | — | — | EP | disclosed |
| WO-2006102007-A2 | METHODS FOR SYNTHESIZING ALKYLATED AND ALKENYLATED QUINONE DERIVATIVES | SAN DIEGO STATE UNIVERSITY FOUNDATION (US) | 2006-09-28 | — | — | WO | disclosed |
| EP-1603557-A2 | SYNTHESIS OF PELORUSIDE A AND ANALOGS THEREOF FOR USE AS ANTITUMOR AGENTS | BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20040235939-A1 | Synthesis of peloruside a and analogs thereof for use as antitumor agents | UNIVERSITY OF TEXAS SYSTEM, THE | 2004-11-25 | — | — | US | disclosed |
| WO-2004074249-A2 | SYNTHESIS OF PELORUSIDE A AND ANALOGS THEREOF FOR USE AS ANTITUMOR AGENTS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2004-09-02 | — | — | WO | disclosed |
| US-5284976-A | Method of producing primary amines in high yields | ALDRICH CHEMICAL COMPANY, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5276195-A | Process for producing dimethylorganoboranes | ALDRICH CHEMICAL COMPANY, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5214209-A | Method of producing primary amines in high yields and novel intermediates therefor | ALDRICH CHEMICAL COMPANY, INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5210310-A | Optically active dimethylorganoboranes | ALDRICH CHEMICAL CO., INC. (US) | 1993-05-11 | — | — | US | disclosed |
| US-5087700-A | Method of producing primary amines in high yields | ALDRICH CHEMICAL COMPANY, INC. (US) | 1992-02-11 | — | — | US | disclosed |
| US-4918229-A | Method of producing primary amines in high yields and novel intermediates therefor | ALDRICH CHEMICAL COMPANY, INC. (US) | 1990-04-17 | — | — | US | disclosed |