Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498964 | 0.96 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL6570628 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL721744 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL1268551 | 0.75 | — | — | |
| SCHEMBL3738689 | 0.74 | — | — | |
| SCHEMBL8966736 | 0.70 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL1931674 | 0.70 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL27140 | 0.67 | — | — | |
| SCHEMBL370393 | 0.64 | — | — | |
| SCHEMBL7695888 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294814-A1 | METAL COMPLEXES HAVING 4-H, 6-H OR 8-H DIHYDROAZULENYL LIGANDS AND USE THEREOF | Umicore AG & Co. KG (DE) | 2023-12-27 | — | — | EP | disclosed |
| CN-117003630-A | Methods and intermediates for preparing carboprostacyclin analogs | 佳和桂科技股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116917295-A | Metal complexes with 4-H, 6-H or 8-H-dihydroazulene ligands and uses thereof | 优米科尔股份公司及两合公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-2010539-B1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | NEKTAR THERAPEUTICS (US) | 2017-06-14 | — | — | EP | disclosed |
| US-8563726-B2 | Stereoselective reduction of a morphinone | NEKTAR THERAPEUTICS (US) | 2013-10-22 | — | — | US | disclosed |
| US-20130018190-A1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | NEKTAR THERAPEUTICS (US) | 2013-01-17 | — | — | US | disclosed |
| US-8183376-B2 | Stereoselective reduction of a morphinone | NEKTAR THERAPEUTICS (US) | 2012-05-22 | — | — | US | disclosed |
| EP-0876295-B1 | METHODS FOR SYNTHESIS OF NANOSTRUCTURED OXIDES AND HYDROXIDES | UNIV CONNECTICUT (US) | 2009-10-07 | — | — | EP | disclosed |
| US-20090221766-A1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-09-03 | — | — | US | disclosed |
| EP-2010539-A2 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | Nektar Therapeutics AL, Corporation (US) | 2009-01-07 | — | — | EP | disclosed |
| US-5137881-A | Anticholesterol, antilipemic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| US-5120782-A | Treatment of hyperlipoproteinaemia, lipoproteinaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-09 | — | — | US | disclosed |
| US-5076829-A | SUBSTITUTED 2,3-EPOXY-5-CYCLOHEXENONE DERIVATIVES, AND FUNGICIDES AND HERBICIDES CONTAINING SAME | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| US-5075311-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |
| US-5064841-A | HMG-COA reductase-inhibiting imino-substituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| US-5034399-A | Enzyme inhibitors, anticholesterol agents or antilipemic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| US-5032602-A | Inhibiting HMG-CoA reductase with novel substituted 2-pyridones and pyrid-2-thiones | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4988711-A | HMG-CoA reductare-inhibiting N-substituted N-amino-pyrroles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4973598-A | Substituted imidazolinones and imidazolinethiones | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | disclosed |
| US-4000273-A | METHOD FOR THE CONTROL OF FERTILITY | RICHARDSON-MERRELL INC. (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018190-A1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | SORD, ADH1C, ADH1A | TSHR 4662/4885ALDH1A1 57/4885 |
| US-20090221766-A1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | SORD, ADH1C, ADH1A | TSHR 4662/4885ALDH1A1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.