SCHEMBL6570628

SCHEMBL6570628

C=CCB(CC=C)CC=C.[KH]

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498964 0.96 TSHR (0.33) TSHRALDH1A1
SCHEMBL4257968 0.92 TSHR (0.31) TSHRALDH1A1
SCHEMBL721744 0.92 TSHR (0.31) TSHRALDH1A1
SCHEMBL1268551 0.75
SCHEMBL3738689 0.74
SCHEMBL8966736 0.70 TSHR (0.38) TSHRALDH1A1
SCHEMBL1931674 0.70 TSHR (0.33) TSHRALDH1A1
SCHEMBL27140 0.67
SCHEMBL370393 0.64
SCHEMBL7695888 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003630-A Methods and intermediates for preparing carboprostacyclin analogs 佳和桂科技股份有限公司 2023-11-07 CN disclosed
CN-116917295-A Metal complexes with 4-H, 6-H or 8-H-dihydroazulene ligands and uses thereof 优米科尔股份公司及两合公司 2023-10-20 CN disclosed
US-20040073045-A1 Pyrrolidine derivative and process for producing the same EISAI CO., LTD. (JP) 2004-04-15 US disclosed
EP-1375479-A9 PYRROLIDINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Eisai Co., Ltd. (JP) 2004-04-14 EP disclosed
EP-1375465-A1 CYCLOOCTANONE DERIVATIVE AND CYCLODECANONE DERIVATIVE, AND USE THEREOF Eisai Co., Ltd. (JP) 2004-01-02 EP disclosed
US-4255575-A HYPOTENSIVE, ANTISPASMODIC, ADRENERGIC BLOCKING AGENTS RICHARDSON-MERRELL INC. (US) 1981-03-10 US disclosed
US-4239681-A ENHANCE LIBIDO AND RELATED PSYCHIC ATTITUDES RICHARDSON-MERRELL INC. (US) 1980-12-16 US disclosed
US-4206125-A ADENERGIC BLOCKING AGENTS, HYPOTENSIVES RICHARDSON-MERRELL INC. (US) 1980-06-03 US disclosed
US-4200755-A ADRENERGIC BLOCKING AGENTS, ANTISPASMODIC AGENTS, HYPOTENSIVE AGENTS RICHARDSON-MERRELL INC. (US) 1980-04-29 US disclosed
US-4139617-A STEROIDS, ANTIDEPRESSANTS RICHARDSON-MERRELL INC. (US) 1979-02-13 US disclosed
US-4087524-A Androst-4-en-19-ols for the enhancement of libido RICHARDSON-MERRELL INC. (US) 1978-05-02 US disclosed
US-4071625-A 19-Oxygenated-5α-androstanes for the enhancement of libido RICHARDSON-MERRELL INC. (US) 1978-01-31 US disclosed
US-4071624-A Androst-4-en-19-ones for the enhancement of libido RICHARDSON-MERRELL INC. (US) 1978-01-31 US disclosed
US-4022769-A LIBIDO ENHANCEMENT RICHARDSON-MERRELL INC. (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040073045-A1 Pyrrolidine derivative and process for producing the same DHPS, SQLE, FDFT1 TSHR 4497/4885ALDH1A1 697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.