Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498964 | 0.96 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL4257968 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL6570628 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL1268551 | 0.75 | — | — | |
| SCHEMBL3738689 | 0.74 | — | — | |
| SCHEMBL8966736 | 0.70 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL1931674 | 0.70 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL27140 | 0.67 | — | — | |
| SCHEMBL370393 | 0.64 | — | — | |
| SCHEMBL7695888 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130580-A1 | PREPARATION OF DEUTERATED VENLAFAXINES | Auspex Pharmaceuticals, Inc. (US) | 2017-02-15 | — | — | EP | claimed |
| WO-2012004811-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-01-12 | — | — | WO | claimed |
| EP-2125698-A1 | DEUTERATED VENLAFAXINES AND 0-DESMETHYLVENLAFAXINES WITH SEROTONINERGIC AND /OR NOREPINEPHRINERGIC ACTIVITY | Auspex Pharmaceuticals, Inc. (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008140859-A1 | DEUTERATED VENLAFAXINES AND 0-DESMETYLVENLAFAXINES WITH SEROTONINERGIC AND / OR NOREPINEPHRINERGIC ACTIVITY | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | claimed |
| US-20080234257-A1 | SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | US | claimed |
| US-6670515-B1 | Hydrogenation or coupling catalysts; reduced agglomeration; increased life; stronger support attachment; efficiency | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-12-30 | — | — | US | claimed |
| EP-1135209-B1 | MATERIAL CONSTITUTED BY METAL PARTICLES AND ULTRAFINE OXIDE PARTICLES | CENTRE NAT RECH SCIENT (FR) | 2003-01-08 | — | — | EP | claimed |
| US-6395900-B1 | N-DEPROTECTION AND/OR O-DEMETHYLATION OF AN OPIOID COMPOUND OR OF A NONPEPTIDIC DELTA TERT-AMIDE AGONIST WITH A LITHIUM TRIALKYLBOROHYDRIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2002-05-28 | — | — | US | claimed |
| US-20020045755-A1 | Novel methods of O-demethylation and N-deprotection | COOP ANDREW (US) | 2002-04-18 | — | — | US | claimed |
| EP-0912577-A2 | NOVEL METHODS OF O-DEMETHYLATION AND N-DEPROTECTION | THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services (US) | 1999-05-06 | — | — | EP | claimed |
| WO-1997044317-A9 | NOVEL METHODS OF O-DEMETHYLATION AND N-DEPROTECTION | — | 1998-06-25 | — | — | WO | claimed |
| WO-1997044317-A2 | NOVEL METHODS OF O-DEMETHYLATION AND N-DEPROTECTION | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-11-27 | — | — | WO | claimed |
| EP-0503923-B1 | Synthesis of 1 alpha-hydroxy-secosterol compounds | WISCONSIN ALUMNI RES FOUND (US) | 1994-12-28 | — | — | EP | claimed |
| EP-0503923-A1 | Synthesis of 1 alpha-hydroxy-secosterol compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1992-09-16 | — | — | EP | claimed |
| CN-111826160-B | Cadmium-free quantum dot, method of manufacturing the same, composition, quantum dot polymer composite, and display device including the same | 三星电子株式会社 | 2024-05-14 | — | — | CN | disclosed |
| US-11901178-B2 | Quantum dots and production method thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2024-02-13 | — | — | US | disclosed |
| EP-4294814-A1 | METAL COMPLEXES HAVING 4-H, 6-H OR 8-H DIHYDROAZULENYL LIGANDS AND USE THEREOF | Umicore AG & Co. KG (DE) | 2023-12-27 | — | — | EP | disclosed |
| US-4082810-A | STEREOSELECTIVE HYDROGENATING AGENTS | ALDRICH-BORANES, INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4051248-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, NEUROLEPTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-4000273-A | METHOD FOR THE CONTROL OF FERTILITY | RICHARDSON-MERRELL INC. (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045755-A1 | Novel methods of O-demethylation and N-deprotection | OPRD1, OPRM1, OPRK1 | TSHR 1459/4885ALDH1A1 363/4885 |
| US-20080234257-A1 | SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY | SLC6A4, HTR4, GPR34 | TSHR 1125/4885ALDH1A1 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.