Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | SYK | P43405 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554225 | 0.76 | NOTUM (0.58) | POLBSYKNPC1RAB9AKMT2A | |
| SCHEMBL4892738 | 0.76 | AOC2 (0.50) | POLBNPC1RAB9AGPR35MAPT | |
| SCHEMBL11858223 | 0.75 | GPR35 (0.67) | POLBGPR35MAPTKMT2AMEN1 | |
| SCHEMBL4457861 | 0.75 | S1PR1 (0.47) | POLBNPC1RAB9AMAPTKMT2A | |
| SCHEMBL14981681 | 0.75 | SYK (0.41) | ACLYSYK | |
| SCHEMBL23214242 | 0.74 | S1PR1 (0.50) | POLBSYKMAPTCYP3A4ALDH1A1 | |
| SCHEMBL31133426 | 0.74 | KMT2A (0.54) | POLBMAPTKMT2AMEN1USP2 | |
| SCHEMBL25319314 | 0.73 | MAPT (0.68) | POLBNPC1RAB9AMAPTKMT2A | |
| SCHEMBL14961833 | 0.73 | ACLY (0.39) | ACLYPOLBSYKNPC1RAB9A | |
| SCHEMBL14981480 | 0.72 | SYK (0.39) | ACLYSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |