SCHEMBL4456482

SCHEMBL4456482

CC(CC=O)c1ccccc1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
CA2 P00918 1/20 0.32
TP53 P04637 1/20 0.32
RIPK1 Q13546 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21176955 0.83 ALDH1A1 (0.34) ALDH1A1TSHRCYP3A4CYP2C19
SCHEMBL24620116 0.77 TSHR (0.55) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL473489 0.77 GABRA1 (0.40) TSHRCYP3A4CA2
SCHEMBL12290677 0.76 ESR1 (0.42) ALDH1A1TSHRCYP3A4CYP2C19CA2
SCHEMBL6341623 0.76 ALDH1A1 (0.39) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL29892221 0.76 ALDH1A1 (0.39) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL17755070 0.74 ADRB2 (0.42) ALDH1A1TSHRTDP1CYP3A4
SCHEMBL17755323 0.74 HTT (0.42) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL18726501 0.74 CYP3A4 (0.41) ALDH1A1TSHRCYP3A4
SCHEMBL29290994 0.74 ALDH1A1 (0.39) ALDH1A1TSHRTDP1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116847825-A Perfume delivery composition 塔明克私人有限公司 2023-10-03 CN disclosed
EP-1524289-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-16 EP disclosed
US-20070149639-A1 Polymerizable composition, optical material comprising the composition and method for producing the material HORIKOSHI HIROSHI 2007-06-28 US disclosed
EP-1524289-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-04-20 EP disclosed
US-20040254258-A1 Polymerizable composition, optical material comprising the composition and method for producing the material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2004-12-16 US disclosed