SCHEMBL4456485

SCHEMBL4456485

Clc1cccc(-c2ccc(Cl)c(Cl)c2)c1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.67
ALOX5 P09917 1/20 0.57
CYP1B1 Q16678 1/20 0.56
TAAR1 Q96RJ0 2/20 0.55
TP53 P04637 1/20 0.52
ESR2 Q92731 2/20 0.52
MAOB P27338 2/20 0.50
CNR1 P21554 1/20 0.49
BACE1 P56817 1/20 0.46
PGR P06401 2/20 0.44
JAK2 O60674 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776922 1.00 AHR (0.67) AHRALOX5CYP1B1TAAR1TP53
SCHEMBL8652196 0.94 AHR (0.58) AHRALOX5CYP1B1TAAR1TP53
Urea SCHEMBL29106824 0.88 CNR1 (0.53) AHRALOX5CYP1B1TAAR1ESR2
SCHEMBL31491189 0.85 TAAR1 (0.71) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL16394285 0.85 TAAR1 (0.71) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL817554 0.84 ALOX5 (0.65) ALOX5TAAR1TP53ESR2MAOB
SCHEMBL31222672 0.84 ALOX5 (0.65) ALOX5TAAR1TP53ESR2MAOB
SCHEMBL20669453 0.82 TAAR1 (0.68) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL9486784 0.82 ALOX5 (0.53) AHRALOX5TAAR1ESR2MAOB
Hydrochloric Acid SCHEMBL31070804 0.82 ALOX5 (0.62) ALOX5TAAR1TP53ESR2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-12492935-B2 Cavitation state identification method driven by vibration data of fluid machinery ZHEJIANG UNIVERSITY (CN) 2025-12-09 US disclosed
CN-221811292-U Scalable ancient campsite lamp with light switching function 深圳市傲柏科技有限公司 2024-10-08 CN disclosed
CN-118703551-A Application of Chinese wild rice ZlRc and ZlRd gene polymerization in improving polyphenol content of rice seeds 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) 2024-09-27 CN disclosed
US-20240226160-A9 ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) 2024-07-11 US disclosed
CN-114110531-B Electronic device with visual feedback 苹果公司 2024-05-24 CN disclosed
CN-113129799-B Display device and multi-screen display device including the same 乐金显示有限公司 2024-05-03 CN disclosed
US-20240131072-A1 ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) 2024-04-25 US disclosed
CN-114414933-B Inspection device capable of simultaneously plugging multiple interfaces of computer 苏州浪潮智能科技有限公司 2024-02-02 CN disclosed
US-20240035467-A1 CAVITATION STATE IDENTIFICATION METHOD DRIVEN BY VIBRATION DATA OF FLUID MACHINERY ZHEJIANG UNIVERSITY (CN) 2024-02-01 US disclosed
CN-114512519-A Light emitting display apparatus and multi-screen display apparatus including the same 乐金显示有限公司 2022-05-17 CN disclosed
CN-114414933-A Inspection device capable of simultaneously plugging and unplugging multiple interfaces of computer 苏州浪潮智能科技有限公司 2022-04-29 CN disclosed
CN-114110531-A Electronic device with visual feedback 苹果公司 2022-03-01 CN disclosed
US-20210317407-A1 METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS Seattle Children's Hospital (dba Seattle Children's Research Institute) 2021-10-14 US disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20200087399-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) 2020-03-19 US disclosed
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 WO disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087399-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS PHOSPHO1, LCAT, CD47 AHR 765/4885ALOX5 662/4885CYP1B1 4745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.