Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | FBP1 | P09467 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466206 | 0.89 | KMT2A (0.38) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4457150 | 0.85 | MEN1 (0.44) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4457144 | 0.85 | MEN1 (0.44) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4469855 | 0.85 | RAB9A (0.43) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4455255 | 0.85 | RAB9A (0.43) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4464061 | 0.85 | RAB9A (0.43) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4469735 | 0.73 | RAB9A (0.40) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4469739 | 0.73 | RAB9A (0.40) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4456549 | 0.71 | RAB9A (0.38) | KMT2AMEN1POLBCASP6ALDH1A1 | |
| SCHEMBL4452906 | 0.70 | RAB9A (0.48) | KMT2AALDH1A1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |