Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457144 | 1.00 | MEN1 (0.44) | MEN1KMT2APOLBCASP6NPC1 | |
| SCHEMBL4469735 | 0.88 | RAB9A (0.40) | MEN1KMT2APOLBCASP6NPC1 | |
| SCHEMBL4469739 | 0.88 | RAB9A (0.40) | MEN1KMT2APOLBCASP6NPC1 | |
| SCHEMBL4456544 | 0.85 | KMT2A (0.43) | MEN1KMT2APOLBCASP6NPC1 | |
| SCHEMBL4452906 | 0.83 | RAB9A (0.48) | KMT2ANPC1RAB9AGAAMAPT | |
| SCHEMBL4452838 | 0.83 | RAB9A (0.48) | KMT2ANPC1RAB9AGAAMAPT | |
| SCHEMBL4452847 | 0.83 | RAB9A (0.48) | KMT2ANPC1RAB9AGAAMAPT | |
| SCHEMBL4464811 | 0.75 | MEN1 (0.42) | MEN1KMT2APOLBCASP6NPC1 | |
| SCHEMBL4466206 | 0.73 | KMT2A (0.38) | MEN1KMT2APOLBCASP6NPC1 | |
| SCHEMBL4456549 | 0.73 | RAB9A (0.38) | MEN1KMT2APOLBCASP6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |