SCHEMBL4456565

SCHEMBL4456565

CCC(O)(CC)C(=O)c1ccc(C(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP5 P45974 1/20 0.47
CYP2C9 P11712 2/20 0.46
CYP2D6 P10635 1/20 0.46
HIF1A Q16665 1/20 0.46
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 6/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 3/20 0.41
RAB9A P51151 3/20 0.41
POLB P06746 2/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
HPGD P15428 2/20 0.40
NPC1 O15118 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MITF O75030 1/20 0.38
MAPT P10636 1/20 0.38
FASN P49327 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6702050 0.87 USP5 (0.41) USP5CYP2C9CYP2D6HIF1AMEN1
SCHEMBL4453109 0.85 USP5 (0.47) USP5CYP2C9CYP2D6HIF1AMEN1
SCHEMBL10939967 0.80 CES2 (0.44) RAB9A
SCHEMBL6692195 0.80 ALDH1A1 (0.44) KMT2AHTTALDH1A1LMNARAB9A
SCHEMBL4469892 0.79 CA2 (0.55) MEN1KMT2AHTTSMN1; SMN2ALDH1A1
SCHEMBL54909 0.79 CYP2C9 (0.50) USP5CYP2C9CYP2D6HIF1AMEN1
SCHEMBL4457079 0.77 ALDH1A1 (0.55) MEN1KMT2AHTTSMN1; SMN2ALDH1A1
SCHEMBL22660971 0.76 USP5 (0.46) USP5CYP2C9CYP2D6HIF1AMEN1
SCHEMBL4556750 0.76 CES1 (0.50) CYP2D6MEN1KMT2AHTTSMN1; SMN2
SCHEMBL12632153 0.76 CYP2C9 (0.50) USP5CYP2C9CYP2D6HIF1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1760102-B1 CATIONICALLY PHOTOPOLYMERIZABLE COMPOSITION AND OPTOELECTRONIC COMPONENT USING SAME THREE BOND CO LTD (JP) 2013-04-24 EP disclosed
EP-2065444-A1 PHOTOPOLYMERIZABLE COMPOSITION THREE BOND CO., LTD. (JP) 2009-06-03 EP disclosed
EP-1760102-A1 CATIONICALLY PHOTOPOLYMERIZABLE COMPOSITION AND OPTOELECTRONIC COMPONENT USING SAME THREE BOND CO., LTD. (JP) 2007-03-07 EP disclosed
US-4902725-A Photocurable acrylic coating composition GENERAL ELECTRIC COMPANY (US) 1990-02-20 US disclosed
EP-0274595-A2 Aromatic carbonate resin articles coated with a photocured acrylic coating GENERAL ELECTRIC COMPANY (US) 1988-07-20 EP disclosed