SCHEMBL445671

SCHEMBL445671

c1cc(-c2cc(-c3ccncc3)cc(-c3ccncc3)c2)ccn1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.79
LMNA P02545 1/20 0.79
NOTUM Q6P988 1/20 0.61
QDPR P09417 1/20 0.52
KIF11 P52732 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
PABPC1 P11940 1/20 0.48
APOBEC3A P31941 1/20 0.48
EIF4H Q15056 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
DDAH1 O94760 1/20 0.47
NOS1 P29475 1/20 0.47
TP53 P04637 1/20 0.46
PKM P14618 1/20 0.46
CYP17A1 P05093 2/20 0.45
CYP21A2 P08686 2/20 0.45
CYP11B1 P15538 2/20 0.45
PRKCI P41743 1/20 0.44
AAK1 Q2M2I8 1/20 0.44
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14426233 1.00 MAPT (0.79) MAPTLMNANOTUMQDPRKIF11
SCHEMBL12068482 1.00 MAPT (0.79) MAPTLMNANOTUMQDPRKIF11
SCHEMBL13915993 1.00 MAPT (0.79) MAPTLMNANOTUMQDPRKIF11
SCHEMBL18748287 0.97 MAPT (0.73) MAPTLMNANOTUMQDPRKIF11
SCHEMBL13907332 0.97 MAPT (0.73) MAPTLMNANOTUMQDPRKIF11
SCHEMBL19270240 0.97 MAPT (0.73) MAPTLMNANOTUMQDPRKIF11
SCHEMBL13907285 0.97 MAPT (0.73) MAPTLMNANOTUMQDPRKIF11
SCHEMBL9728 0.89 MAPT (1.00) MAPTLMNANOTUMQDPRKIF11
SCHEMBL12068479 0.88 MAPT (0.61) MAPTLMNANOTUMQDPRKIF11
SCHEMBL12452342 0.88 NOTUM (0.65) MAPTLMNANOTUMQDPRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080437-A Flexible metal-organic framework material with humidity response and preparation method and application thereof 2026-05-26 CN claimed
CN-118359823-B Flexible MOFs material capable of inducing amorphous conversion by reversible water, preparation method and light modulation and control application thereof 南开大学 2025-05-09 CN claimed
CN-119909659-A Preparation of SF by using amino-functionalized pore segmentation strategy6Method for adsorbing material 国网吉林省电力有限公司白山供电公司 2025-05-02 CN claimed
CN-119746830-A Preparation method, adsorption and desorption method of lithium isotope adsorbent 中国科学院青海盐湖研究所 2025-04-04 CN claimed
CN-119287460-B Copper electroplating leveling agent, preparation method thereof, electroplating solution, electroplating method and product 深圳市联合蓝海应用材料科技股份有限公司 2025-03-14 CN claimed
CN-119528801-A Quaternary ammonium salt compound taking tripyridyl benzene as framework and preparation method thereof 深圳市联合蓝海应用材料科技股份有限公司 2025-02-28 CN claimed
CN-119463170-A Preparation method and application of triazinyl ionic organic polymer 昆明理工大学 2025-02-18 CN claimed
CN-119368023-A Polyether block polyamide hybrid membrane based on modified hydrogen bond organic framework filling and preparation method and application thereof 天津大学 2025-01-28 CN claimed
CN-119287460-A Copper electroplating leveling agent, preparation method thereof, electroplating solution, electroplating method and product 深圳市联合蓝海应用材料科技股份有限公司 2025-01-10 CN claimed
CN-118638285-B CO (carbon monoxide)2Porous bifunctional catalyst for cycloaddition reaction, and preparation method and application thereof 中国矿业大学 2025-01-10 CN claimed
CN-117209516-A Boron-amine complex monomer with strong charge separation, boron-amine conjugated polymer, and preparation method and application thereof 上海科技大学 2023-12-12 CN claimed
CN-115206688-A Preparation method and application of nano metal phosphide 中国石油大学(华东) 2022-10-18 CN claimed
US-9207234-B2 Thermally stable SERS taggants SICPA HOLDING SA (CH) 2015-12-08 US claimed
EP-2519467-A1 MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF Colorado State University Research Foundation (US) 2012-11-07 EP claimed
EP-2433121-A1 THERMALLY STABLE SERS TAGGANTS Cabot Security Materials Inc. (US) 2012-03-28 EP claimed
US-20120062886-A1 Thermally Stable SERS Taggants CABOT SECURITY MATERIALS INC. (US) 2012-03-15 US claimed
US-8063207-B2 Molecular assembly KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2011-11-22 US claimed
WO-2011082164-A1 MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-07-07 WO claimed
US-20110159116-A1 BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-06-30 US claimed
WO-2010135351-A1 THERMALLY STABLE SERS TAGGANTS OXONICA MATERIALS INC. (US) 2010-11-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110159116-A1 BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES NOS2, NOS3, NOS1 MAPT 3380/4885LMNA 4024/4885NOTUM 2065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.