SCHEMBL4456789

SCHEMBL4456789

Cc1cc(Cc2ccc(O)cc2C=O)c(O)c(Cc2ccc(O)cc2C=O)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.49
ERN1 O75460 3/20 0.47
SRC P12931 1/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HSPA5 P11021 1/20 0.41
CYP2D6 P10635 1/20 0.36
HSD17B10 Q99714 1/20 0.36
IDH1 O75874 2/20 0.35
ALOX5 P09917 1/20 0.34
TRIM24 O15164 1/20 0.33
TYR P14679 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
EGFR P00533 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL210156 0.79 ERN1 (0.69) AMY1AERN1SRCCYP2C9CYP2C19
SCHEMBL31612188 0.79 ERN1 (0.69) AMY1AERN1SRCCYP2C9CYP2C19
SCHEMBL4564731 0.79 TNKS (0.36) ALOX5MEN1MAPTKMT2A
SCHEMBL4061742 0.78 AMY1A (0.56) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4004589 0.78 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4059100 0.78 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4055159 0.78 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4063293 0.78 AMY1A (0.56) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30703618 0.78 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29951036 0.77 SRC (0.44) ERN1SRCALOX5TRIM24TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7586009-B2 Bis-(hydroxybenzaldehyde) compound and novel polynuclear polyphenol compound derived therefrom and method for production thereof HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-08 US disclosed
US-7586009-B2 Bis-(hydroxybenzaldehyde) compound and novel polynuclear polyphenol compound derived therefrom and method for production thereof HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-08 US disclosed
US-7586009-B2 Bis-(hydroxybenzaldehyde) compound and novel polynuclear polyphenol compound derived therefrom and method for production thereof HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-08 US disclosed
US-20090076310-A1 NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-03-19 US disclosed
US-20090076310-A1 NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-03-19 US disclosed
US-20090076310-A1 NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076310-A1 NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF DDT, PAH, HPD AMY1A 4533/4885ERN1 4774/4885SRC 3564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.