SCHEMBL4456940

SCHEMBL4456940

C=C(C)C(=O)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(C)(F)F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328346 1.00 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL434896 1.00 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL1369440 1.00 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL36676 0.98 ALDH1A1 (0.38) ALDH1A1TSHR
Methacrylic Acid SCHEMBL10493561 0.93 ALDH1A1 (0.34) ALDH1A1
SCHEMBL87496 0.92 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL4603430 0.92 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL15157271 0.87 ALDH1A1 (0.35) ALDH1A1
SCHEMBL5084731 0.86 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL535043 0.86 ALDH1A1 (0.38) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
WO-2024086390-A2 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-25 WO disclosed
EP-4249519-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. (US) 2023-09-27 EP disclosed
US-7495037-B2 Dental coating materials IVOCLAR VIVADENT AG (LI) 2009-02-24 US disclosed
EP-0851246-B1 Optical fiber clad with low refractive index photocured composition LUCENT TECHNOLOGIES INC (US) 2008-12-10 EP disclosed
US-20050165129-A1 Dental coating materials IVOCLAR VIVADENT AG (LI) 2005-07-28 US disclosed
EP-0890131-A2 PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ALLIANT TECHSYSTEMS INC. (US) 1999-01-13 EP disclosed
US-5856430-A Process and materials for inducing pre-tilt in liquid crystals and liquid crystal displays ALLIANT TECHSYSTEMS INC. (US) 1999-01-05 US disclosed
US-5822489-A CLADDING ON OPTICAL FIBER MADE OF A CURED MATERIAL COMPRISING A PERFLUOROPOLYETHER OR PERFLUOROHYDROCARBON BACKBONE END CAPPED WITH (METH)ACRYLATE GROUPS VIA URETHANE GROUPS LUCENT TECHNOLOGIES, INC. (US) 1998-10-13 US disclosed
EP-0851246-A1 Optical fiber clad with low refractive index photocured composition LUCENT TECHNOLOGIES INC. (US) 1998-07-01 EP disclosed
WO-1997037273-A2 PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ALLIANT TECHSYSTEMS INC. (US) 1997-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050165129-A1 Dental coating materials PHOSPHO1, SPTAN1, ITGA1 ALDH1A1 2568/4885TSHR 4370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.