Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21831203 | 0.87 | NR3C1 (0.44) | CES2CES1CA12CA1CA9 | |
| SCHEMBL12065137 | 0.85 | IDO1 (0.50) | CES2CES1CA12CA1CA9 | |
| SCHEMBL230516 | 0.83 | CES2 (0.50) | CES2CES1IDO1TDO2SLC6A2 | |
| SCHEMBL28274632 | 0.77 | CES2 (0.46) | CES2CES1CA12CA1CA9 | |
| SCHEMBL4066383 | 0.77 | CES2 (0.46) | CES2CES1CA12CA1CA9 | |
| SCHEMBL4094087 | 0.77 | CES2 (0.46) | CES2CES1CA12CA1CA9 | |
| SCHEMBL1321039 | 0.77 | CES2 (0.46) | CES2CES1CA12CA1CA9 | |
| SCHEMBL1154665 | 0.77 | CES2 (0.46) | CES2CES1CA12CA1CA9 | |
| SCHEMBL14992168 | 0.76 | POLB (0.35) | CES2CES1 | |
| SCHEMBL8078157 | 0.74 | CES2 (0.37) | CES2CES1CYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443083-B1 | Pearlescent pigments based on selectively absorbing layers of chalcogenide, oxychalcogenide and mixed chalcogenides | MERCK PATENT GMBH (DE) | 2008-02-27 | — | — | EP | claimed |
| EP-3850594-B1 | VALUABLE DOCUMENT SYSTEM | GIESECKE & DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) | 2026-03-11 | — | — | EP | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| EP-3850594-A1 | VALUABLE DOCUMENT SYSTEM | Giesecke+Devrient Currency Technology GmbH (DE) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020052812-A1 | VALUABLE DOCUMENT SYSTEM | GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) | 2020-03-19 | — | — | WO | disclosed |
| US-7576088-B2 | Benzodioxole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1490691-B1 | LUMINESCENT, SPHEROID, NON-AUTOFLUORESCENT SILICA GEL PARTICLES HAVING VARIABLE EMISSION INTENSITIES AND FREQUENCIES | MAGNAMEDICS GMBH (DE) | 2009-01-21 | — | — | EP | disclosed |
| EP-1532132-B1 | NOVEL BENZODIOXOLES | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | disclosed |
| US-20050143373-A1 | Benzodioxole derivatives | ALANINE ALEXANDER (FR) | 2005-06-30 | — | — | US | disclosed |
| US-6900227-B2 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| EP-1490691-A2 | LUMINESCENT, SPHEROID, NON-AUTOFLUORESCENT SILICA GEL PARTICLES HAVING VARIABLE EMISSION INTENSITIES AND FREQUENCIES | Müller-Schulte, Detlef P. (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-20040142922-A1 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |
| WO-2003083481-A2 | LUMINESCENT, SPHEROID, NON-AUTOFLUORESCENT SILICA GEL PARTICLES HAVING VARIABLE EMISSION INTENSITIES AND FREQUENCIES | MUELLER-SHULTE DETLEF P (DE) | 2003-10-09 | — | — | WO | disclosed |
| US-5153211-A | Enzyme inhibitors | ALCON LABORATORIES, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5070100-A | COMPLICATIONS OF DIABETES | ALCON LABORATORIES, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-4864028-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1989-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143373-A1 | Benzodioxole derivatives | CNR2, CNR1, GPR119 | CES2 197/4885CES1 229/4885CA12 3791/4885 |
| US-20040142922-A1 | Benzodioxole derivatives | CNR1, CNR2, GPR119 | CES2 214/4885CES1 47/4885CA12 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.