SCHEMBL4457115

SCHEMBL4457115

O=S(=O)(c1ccccc1)C(Br)(Br)Br.O=S(=O)(c1ccccn1)C(Br)(Br)Br

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
PKM P14618 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
PTGS2 P35354 1/20 0.38
ALDH1A1 P00352 6/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 1/20 0.38
NFE2L2 Q16236 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
LOX P28300 1/20 0.36
GLO1 Q04760 1/20 0.36
SLC40A1 Q9NP59 1/20 0.36
HTR6 P50406 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904752 0.91 KDM4E (0.47) KDM4EPKML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL542032 0.91 KDM4E (0.47) KDM4EPKML3MBTL1SMN1; SMN2ALDH1A1
Benzene SCHEMBL8203386 0.80 HTR6 (0.52) PKMKMT2ASMN1; SMN2ALDH1A1TDP1
SCHEMBL152444 0.80 HTR6 (0.52) PKMKMT2ASMN1; SMN2ALDH1A1TDP1
SCHEMBL4640457 0.80 HTR6 (0.52) PKMKMT2ASMN1; SMN2ALDH1A1TDP1
Methane SCHEMBL29092261 0.78 HTR6 (0.50) PKMKMT2ASMN1; SMN2ALDH1A1TDP1
Silver SCHEMBL7967941 0.76 HTR6 (0.48) PKMKMT2ASMN1; SMN2ALDH1A1TDP1
SCHEMBL1573626 0.75 KDM4E (0.72) KDM4EPKML3MBTL1KMT2ASMN1; SMN2
SCHEMBL24995386 0.73 KDM4E (0.46) KDM4EPKML3MBTL1ALDH1A1NFE2L2
SCHEMBL3983033 0.73 KDM4E (0.50) KDM4EPKML3MBTL1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7514206-B2 Thermally developable materials with buried conductive backside coatings CARESTREAM HEALTH, INC. (US) 2009-04-07 US disclosed
US-20070244004-A1 Thermally developable materials with buried conductive backside coatings EASTMAN KODAK COMPANY 2007-10-18 US disclosed
US-7258968-B1 Thermally developable materials with buried conductive backside coatings CARESTREAM HEALTH, INC. (US) 2007-08-21 US disclosed
EP-1631456-A2 1-4-DIHYDROPYRIDINE-CONTAINING IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PRODUCTION OF IMAGEABLE ELEMENTS Kodak Polychrome Graphics GmbH (DE) 2006-03-08 EP disclosed
WO-2005001571-A2 1-4-DIHYDROPYRIDINE-CONTAINING IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PRODUCTION OF IMAGEABLE ELEMENTS KODAK POLYCHROME GRAPHICS GMBH (DE) 2005-01-06 WO disclosed