SCHEMBL4457326

SCHEMBL4457326

CCCO[Si](CCCOC(C)=S)(OCCC)OCCC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333330 0.86 CA12 (0.32) CA12CA1CA2CA9ALDH1A1
SCHEMBL1224891 0.81 ALDH1A1 (0.57) ALDH1A1
SCHEMBL333406 0.79 CA12 (0.36) CA12CA1CA2CA9
SCHEMBL333539 0.79 CA12 (0.36) CA12CA1CA2CA9
SCHEMBL333506 0.79 CA12 (0.36) CA12CA1CA2CA9
SCHEMBL333701 0.78 LMNA (0.33) CA12CA1CA2CA9
SCHEMBL10591430 0.77 ALDH1A1 (0.38) ALDH1A1
SCHEMBL702188 0.76 LMNA (0.31)
SCHEMBL431790 0.76 LMNA (0.31)
SCHEMBL72841 0.75 TSHR (0.59) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090143538-A1 Silane-Coupling-Agent-Treated Silica, Preparation Method Thereof, And Vibration-Damping And Vibration-Isolating Rubber Composition Containing The Same DOW CORNING TORAY CO., LTD. (JP) 2009-06-04 US disclosed
EP-1805254-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME Dow Corning Toray Co., Ltd. (JP) 2007-07-11 EP disclosed
WO-2006016714-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO disclosed